I'm david poke from CBS Sunday morning. The world may have problems, but it's so got geniuses working to solve those problems through science and technology. In the new season of my podcast unsung science you'll hear the origin stories of their greatest advances season, two of unsung science presented by sea bs sunday morning and simon and choose to listen unsung science starting january twentieth on amazon, music or wherever you get your broadcasts? Sixty minutes has travel to a lot of far our places to tell a lot of incredible stories. But on this trip to the colombian countryside, we ran smack into a mess. detective story that man up affecting someone you know and love after years of research on a unique population of patients multi million dollar an age back study- has begun wit to see if the dreaded

timers disease may be preventable if it makes a difference for them. I think this is a reasonable chance. It could make a difference for all the rest of the people who get alzheimer's disease. I didn't feel entitled to become a star. I didn't expect it did you want it really. Britain, France, did not around hollywood for decades before landing his first leading role at age. Fifty then transformation walter white on breaking back. I am the danger, a tough act to follow yet somehow the hell is this he managed to do weighing president Lyndon Johnson were making history here effort and you have to decide how you won't history. Remember you I'm steve cry. I'm leslie star, I'm bill whittaker, I'm anderson cooper, I'm scott pelee! Those

worries tonight on sixty minutes. A new gas network featuring radio and tv personalities, talking business, sports, tack, entertainment and more players died in nobel prize winning colombia, novelist, Gabrielle, see a mark has once wrote a mythical town in the middle of the jungle whose residents suffer from a mysterious affliction that erases their memories, today in a region of colombia called anti. Ok, a reality appears to be imitating fiction in a way that may answer questions for all of us. As we first reported last fall anti, here is home to the largest concentration in the world of people who carry a rare genetic mutations that makes them one hundred percent certain to develop alzheimer's disease and its devastating as alzheimer's is anywhere. This is a particularly cruel version.

strikes when people are in their mid fortys and lisa death about a decade later. It is a tragic situation, but a perfect scientific labour, for you and it's now the centre of a multi million dollar, and I urge back study trying to find out for the first time whether all seiners disease may be preventable. These are the andes, mountains and lush countryside of anti. Ok, a colombia whose cap city. Marrying was once famous for murder and the drug cartel pablo Escobar today, marrying or Jeanne as its pronounced here is peaceful but for some families here, they're still, A battle going on a battle against insidious disease. This family, mother, cecilia per se,

in children and grandchildren lost its patriarch. Alonso me my fire was number one friday. The oldest remembers his dad. Ways eager to join in and play with him and his friends from a movie. I legatee he was a very joyful person, he loved to dance around a bizarre mc. He was a really nice person, a very good father and that they have had me before the disease When I first started what were you noticing that made? You think he's he's different in this article goodbye it. I won't he started asking what is the day to day? Do I have to go to work jennifer and we got concerned along so at the time was in his mid forties saw them.

we lost and confusion made. No sense his doctor suggested exercise and vitamins, but Alonso just got worse, forgetting the names of his children getting lost and disoriented. His son victor had to help him get dressed linda. You luck, I'm isa. I gave him his shirt and I told him dad com one I'll help. You put your shirt on eloping middle case with oil, and the first thing he did was to grab it important set up. One must be and put it on through his feet. Did he understand what was happening to him a moment of pollution? Is There were moments of lucidity and commit. They were dying where he would May I say son what's happening to me for another question Why don't? I remember not accorded let whose I dont remember my children or my wife? No second, so I dont know why

Your son hullo took him back to see the doctor combine a perimeter looked on ahead of thought. When I asked the doktor, I told him doctor, I'm not leaving here either. A statue will stand yahkuk than anybody until you me: what is wrong with my father? The doktor sent them to francisco low para a neurologist at the university of anti ogier who knew exactly what was long with alonso, because he'd become the local authority on a rash early answered all seiners cases in and around marrying they well yet in disease betty early in life, it all began many years earlier back in the nineteen eighties, when low para was a young medical resident, he had read about small numbers of peoples.

added around the world who developed alzheimer's in their forties, so a forty seven year old man came into his medeon clinic with alzheimer's like symptoms, he was intrigue and decided to investigate. New met this one man and you decided to go to waste. the driver to the town where he was leaving low para learn that the man's father and grandfather had also lost their memories in their forties. Then, a few years later, another similar patient came into the clinic. This time forty two year old woman from a town, forty miles away doctoral, appear as then a sluice see a madrigal asked if any of her relatives also I started, losing their memories when they were young, no control, because he killed papa close to your skill, as they told us. Yes, that the father, the uncles, the grandfather, the great grandfather,

then who kept a king, and so I started making a little family tree on one page use animals and I showed it to doktor low para and told him look what we have here. What is this so many with the same disease and so began a detective hunt that lasted more than a decade, Oh para and Madrigal travelled all over the region. Finding more and more people afflicted with early onset, alzheimer's and compiling family trees, they thought it might be genetic, so madrigal spent days at parish, churches worrying over heavy ledgers, where priests for generations had recorded village, births, marriages and deaths. Thanks to these meticulous records, she was able to trace the disease back hundreds of years and to make an important discovery. The different families were actually one huge

standard family connected generations back by common ancestors who had died young with an unusual cause of death. Written down by the priest softening of the brain or no. This is what's funding. The brain looks like in real life. Fernando is forty six years old, a descendant of that second patient years ago, he started forgetting things when he was in his late thirty's, how can no longer speak feed himself out I'm along or do just about anything on his own. She ain't the only real trees. His aunt takes care of him round the clock, just as she did with his mother. When she got the disease,

the same age, nor rally as at an even later stage of the disease. Despite her appearance, she is just fifty eight years old patients were going from mile symptoms to complete dementia and then death within about a decade as dr le paris showed us in these cognitive test results you can see of thirty eight, even at thirty eight, this man struggled as many older alzheimer's patients due to copy a complex drawing accurately at forty five, and things got worse from their us more. Fifty web, ah doctoral au pair, I was convinced that what he and Madrigal were discovering with scientifically important is doing, but even as they

more patience and more related families. He couldn't get anyone outside colombia to take notice until nineteen. Ninety three: when a harvard professor came to give a talk about alzheimer's in bogota several hours away. There a person in the audience, francisco no para who came up after the talk and said you know, there's have a family here, the were: has early onset, alzheimer's can classic now it you see. Santa Barbara was that professor a family could have been for people. Would have been just for people, but he started to tell me how many was and as I listen to him, I became just so absorbed and take it with what he was. Telling me that I changed all my plans went with him to managing and we began to collaboration that goes on to this day. They showed cassock what lucy

a madrigal showed us the family tree they had compiled, based on all that searching through church records for just one of the affected families. Going back all the way the eighteen hundreds, this is one family warner, solar. It just kept unfolding and unfolding covering these pages, are small squares representing men circles for women. The coloured in squares in circles mean the person got sick with alzheimer's at an early age. Look she had these sons, daughter and then it just kept going down through the generations. When we looked at the family trees about fifty some of the offspring, we're getting the disease. That's a clear signature of a gene, but what jean casa connected dil appear with leading geneticists in the u s and they started collecting blood samples and searching

in a year, a major breakthrough, they found a specific muted and in a gene on chromosome fourteen one tiny flaw: in the dna responsible for all this family suffering. The discovery was public. a ninety ninety seven in the journal of the american medical association, low para had identified the largest cause traces of early onset, alzheimer's cases in the world. If a person has that mutation do they get alzheimer's seiners, they do if they haven't they definitely That is right. There are some mutations where you dont definitely get it, but this is a bad one and if you have it Don't you get it for families like alonzo, discovering the mute Station was a blessing, a crucial first step towards finding a way to fight the disease, but it was also occurs because it meant that anyone whose parents have the mutation as a fifty fifty two.

Of having inherited it to do any of you know if you have mutation. Do you now know nobody knows Nobody knows well, somebody knows doktor le para and his team. Testing for the mutation and compiling a database, but their policy is not to tell family members if they have the mutation or but not even to reveal the results to doktor le para. Since at this point there is nothing that can be done to help address it, but I want the quality, but sometimes I ask which one you will get a, but I throw that thought away because I dont want to think about that and which are then you can know you're. I pray a lot to god, that none of them gets it and the kid who, let me see who I don't want to see my children has ever met with that disease. Each one of you knows because of your father that you have a fifty fifty chance.

So. What kind of a wait does that put on you day in and day out later goffredo? Yours, I've even pray to god that if I show you an opportunity for there's one person who has to have the disease that iran is critical, may I say to god Let it be me, though, I think it who impediment I get it. I thank god that I'm a nurse and then I would be able to take care of them, but medium limit the whole calmly papa. I tell myself first, I had to go through with my dad the experience of the disease. May I thank god the current or not, and I may have to go through it with one of my siblings. With several we dont know by Sarah told us she would love to have children of our own, but given her risk of developing the disease, she's decided against it. committee who nothing living in cities, so that my children don't have to through my same experience. You ve been working on for thirty years,

How do you cope with was paying it was not the response we had expected. It's that hard. It's that hard But doktor apparent knew that, even in the midst of all this tragedy, there might just be a glimmer of hope, because what he had discovered in these families, hundreds of people destined to develop balls. farmers and easily identifiable with a simple genetic tests prs.

The unique scientific opportunity to test whether it's possible to step in and stop early onset and maybe all all seiners disease before it starts, welcome to play at a new path. Ass network, featuring radio and tv personalities, talking business, sports, tack, entertainment and more play it play died in. Alzheimer's disease is the sixth leading cause of death in the united states. More than five million americans have alzheimer's right now and given the aid baby boomers population, that number is projected to newly triple by mid century- Yet, unlike many other leading killers, there is no effective treatment and

Alzheimer's diagnosis is essentially a prescription for a slow descent into oblivion and an extra bowl loss of the memories, spatial skills and ability to think that make us who we are early onset ms patients, like the hundreds of family members and colombia, or a tiny fraction of the whole, but to scientists they could be everything because they are offering researchers something they have never had before a way to test whether intervening early before any symptoms start might halt the disease in his tracks. Answers are still Here's away, but with more than a thousand americans developing all farmers every day away to prevent it cannot come soon enough. The scene we win stan doktor pierre terrio exam room at the banner alzheimer's institute in phoenix is one that plays out inequalities,

offices every day, so fires What city were in right now? What would you say, You know right, I don't know at this moment, norm age. Seventy two has been diagnosed with alzheimer's. The typical late in life form. So many of us feel it begins with I own memory and thinking problems and spirals into full on dementia. Who is that young lady over their betsy is sheer friend? Yes how'd, you know betsy, because I loved her it's? Okay, the sheer sister a little bit of both her? Is she your wife and I don't think so? Ok, okay, thank you.

Somebody really good wish. I was I ve been married fifty one years, unlike early set alzheimer's there's been no sir. Jeanne identified, that causes this matter. Sheer knows no wait. I know who among us is destined to get it. What percentage of all people? we're gonna get alzheimer's one. None of us, sixty or older, will have a dimension like alzheimer's disease, but by the time he hit eighty five percent. That percentage is approaching fortyish percent- that's a dogan These are go guns. Alzheimer's disease has been called out by the world health organization as the coming period. of the west. We have to do something to put it behind us. Can you draw? The number, is four o clock but doktor

body, a k was a leading all seiners researcher and clinician at the university of California. Irvine says she's frustrated that she can offer her patients any hope I have to say. I ve been doing this now for a third of a century and when I started I just never would believe we would still not be closer than we are now to making a real difference. It has been a little disappointing, so there it hasn't in for a lack of trying K was gave us a quick primmer on the tell tale signs of alzheimer's in the brain after autopsy they replaced see a brown spot. That is a senile amyloid plaques. In contrast, you see these black things, and to be triangular shape. Those are what we call nerve. Larry tangles, the relationship between plaques entangles, isn't completely understood, but because

that's been shown that amyloid plaques build up in the brain before tangles and years before patients develop symptoms. Do that pharmaceutical company. I have spent hundreds of millions of dollars since the early two thousands developing dry. to remove amyloid from the brain and hundreds of men, and more to test those drugs in patients like norm of all the trials that have been done. What percent have succeeded about? One point in other words, a resounding failure? So what I'd say: do you think well, it says either. Amyloid is not the right thing to go after. or it says we need to remove it earlier on in the process before it's made. All the other things cascade after you know, if you give a polio, seeing one somebody has polio. You can understand why doesn't work you're, saying that maybe those drugs haven't worked because

the person already had alzheimer's exactly and maybe, if we give merrily enough, it might work. But how can you tell drugs on people before they d, up the disease when you don't know who among us is going to get it for more sir under terrio and the executive director at the banner alzheimer's institute, doktor Eric riman realized. There was a place where you could know who going to get all anti. Ok, that's when my phone begun to ring by them. KEN cosmic had been studying. The colombian extended family for fifteen years received a call from the people a banner, and they said you know you have this family. We know when they're gonna get it, we know who's gonna get it. Can we start treating before the disease strikes classic

acted terrio and riman, with doktor le para, who, by that time, had identified hundreds of people who carried the gene mutation, guaranteeing that they would be struck with alzheimer's in the prime of their life. My men and terrio travelled to many and met with both healthy and sick members of the extended family. Is this particular family in the world. An extraordinary there's. Nothing else like the idea that there is this concentrate mission within roughly a hundred miles of each other is just an extraordinary phenomenon and a perfect scientific laboratory to lay the groundwork for a large clinical trial. Banner blue a group of extended family members from many Ain t phoenix for pet scans. One goal to compare the brains of those with without the mutation years, but

any memory loss began when they were in their thirties, ready de riman showed us the results. This is somebody who doesn't have the gene. They have no plaques in the brain, but in members of the family, with a mutation It was a different story: extensive amyloid, deposition in the brain. That's the red read as well I'm a lawyer, but yellow is also. I am on this brain had even more The images showed that amyloid plaques build up in the brain more than it decades before memory loss begins. So if a drug could remove that red and yellow, maybe the disease could be prevented. Banner developed. Plan for a multi million dollar drug trial income, and a meeting with leading scientists, pharmaceutical companies

representatives of the end. I the end of the meeting. Each scientist was allowed to say one closing, thought and francisco have the last word the pair and he paused a long time, and you could hear a pin drop in the room I said to them: we will they. Families are waiting for you. Waiting for you, that's the point where you know the goose bumps came, and we said we really have to make this work. We really do and they did with it It meant a fifteen million dollars from an age, another fifteen million from philanthropists and the rest from drug company genetic. The trial on immunity therapy drug to remove amyloid plaques enrolled its first patient three years ago. And they ve been a rolling more people ever since they told me about this story- and I say yes

go right away on anything that you needed. I'm here, freddy and all his sibling signed up a cable was applied. and is to unroll a total of three hundred members of the extended family who are healthy and No memory loss yet two hundred who have the mutation and another one hundred who don't That way, no one will learn their genetic status. Just by being accepted into the study of the two hundred with the mutation, half will get injections of the drug. The other half will be injected with a harmless placebo. The study is double blow and neither patients nor investigators will know whose getting what they have to come in every two weeks for at least five years long enough to see whether the group taking the drug does better than the group taking placebo final results aren't expected until

when he twenty two. Is this the first time in all these years of seeing these patients that you can actually for then hope he has. This is the first time because it but we only offer their education, better quality of life, but no hope to have a solution, and now they have hope be hope. What, be the best outcome in nobody who receives the immunity therapies, experiences any worsening of their thinking. Your memory ability doesn't change at all, doesn't decline. That would be fabulous, that's a stretch goal, and that would be just the beginning if it makes a difference for them. I think this is a reasonable chance. It could make a difference for all the rest of the people who get alzheimer's disease. Tell me which hand attaching, and that of course is the ultimate goal.

to help prevent the late in life form of alzheimer's that we're all susceptible to the hope is that one day every one of us could be green and when necessary, treated before problems begin? That might be the case that just like, when you go to your doktor, to get your cholesterol checked in your blood to see. If you need drugs to lower your cholesterol, you would go and get an amyloid pet scan and it would be time of routine prevention. We if the drug removes the amyloid and they still get the disease.

I think that a mean that there are other things we need to be targeting besides amyloid, but will you say that the drug test was successful? Hypothesis is to say yes, I think that we need to know the answer. The answer to weather the field focus on amyloid plaques removal for the last fifteen years has been a failure If this test doesn't work, they will at least know they need to go in a different direction. You know, victor all. The other drug trials that have gone on for years have all failed to do. You know that fishing bitter tears had let it you yes, but this is going to be the exception. This is, exception, if it does work, this saves this community wanta, be amazing, be amazing. To me, I'm always impressed These families that come from such a role,

what area of the world have the potential for informing us globally about a path forward for conquering alzheimer's The study is now unrolled all its participants. In the end, I age recently awarded as much as fourteen point eight million dollars in additional funding over the next five years. It's too late, though, for fernando the early onset, all summers patient being cared for by his aunt. He passed away the spring at the age of forty seven from the mona welcomes the play: a new pike, ass network, featuring radio and tv personalities, talking business, sports, tack, entertainment and more play it, play died in of all the actors that pass through hollywood very few, if any that a career like Brian granted, he knocked around tinsel town for decades,

for finally landing use first leading role at age, fifty walter white on breaking bad, a very tough act too far, but stan things for grants than have been breaking good. He wanted A word on broadway, an oscar nomination in hollywood all why writing his memoir? This we first reported last fall. It's all testimony to his talent. Patients, perseverance unlock the room. Princeton was born and raised in los angeles and had been familiar face here for decades. never a store beneficially change. Three years ago, when the hollywood chamber of commerce embedded his name in the sidewalk? I have often walked down the street before the pavement never held my star before, on three stories knowing him on the street, where it lew

since then, really gotten better at aged sixty. He is hollywood a list and a red carpet regular and no one was more surprised, then crest, I didn't feel entitled to become a star? I didn't expect it did you wanted? Not really the things you want professionally are opportunities, and through my good fortune, the What's happened? Opportunity has come to me and when it came late in his career, France didn't knocked it out of the park every you and I could partner up. You want to cook crystal meth. That's right. When we first started, we were just telling a story and trying to do our best and it just started to steam role and became this juggernaut. Did you see it coming now, not at all chemistry

It's a familiar story. Now: a meek and depressed high school chemistry, teacher with terminal cancer, cooks up a scheme to me in market a superior grade of methamphetamine to provide a nest egg for his family after he's gone, but over the course of five seasons. Walter White goes from milk coast to murder, This is why I was just infused with ideas and I would dream about and wake up and go. I have another idea about walter. Why you clearly, now who you're talking to sell them. It was so well written and just got into my soul. I am the danger. It was coincidence first real opportunity to show what he could do was enacted fraud. The result was new respect in a closet full of polemics. When the shoe finally ended, he saw it is a new beginning in an opportunity to try something completely different.

it had been years since crafts and had performed on stage yet he decided to sign on with a theatre. In Boston that was doing a new play called all the way about Lyndon Johnson, a very complicated character. It had to be an amazing challenge. I mean why did you do it? It was shakespearean in size If the rules boy, that's a big bite to take- and it scares me a little bit so let's do it go out and there were reasons to be scared, or I realized Oh, my god, this is an enormous play and its Most all me big big chunks of speeches, speeches beaches and I started panic it is all or nothing but in Boston. we're on broadway and after that, film version for hbo is performed with someone the mark that again, you had to remind yourself. It was crampton Johnson. I love you.

More than my own daddy, but if you get in my way, how crush you look they're after winning a tony award broadways highest on. He talked it off with an oscar nominated performance in the crumble? That's quite a run surprising for an old journeymen actor, got a few clips to show you here. Oh yes, Ok heroic found what the hell is wrong with you creates than has been a working actor senses mid twinning, oh we're very sweet, beginning with part on the soap opera? Loving that attraction is our as an aside and after theirs in everything from the sublime to the ridiculous good guys, bad guys, I'm I'm sorry, we did it

in sometimes ports, so small, even constance forgotten. What is it? cigarettes, amazon, women on the move, five minutes for the winter day. My articulate you it up on the cunning and that's why you never see amazon women on the moon? Who could forget Who wants to remember, isn't the better question actually, but I promised myself in all. There have been nearly one hundred and fifty rolls not counting the early commercials that helped pay the bills. Now you can relate and flame haemorrhoidal tissue with the oxygen action of preparation, age, oxygen, action as it do, you think you ve grown as an actor sensitive nobody, my hemorrhoid, as they were gear spots on just about every show on television, including five appearances on seinfeld is jerry: smarmy dentist, doktor tim waddling, Would you ready the nitrogen oxide links? It was like to comedy bootcamp for me being on that show

in comedy proved to be something that brine grandstand was very good at it, led to his break out, ruled in the widely acclaim series, malcolm in the middle, is how the hapless father overwhelmed by the chaos of this vote no family my weight, something we have to talk about He was in secure, you know not in charge lou. He took brain vacations, often malcolm on plants than a modicum of fame, three emmy nominations and reputation as an actor who was willing to do any. Those are obese, yeah. There's a real bees. There are seventy. Thousand of control gifts. He got stuff. Where were you stuck in the in the lower region? In one of the boys

down below sensitive spot very sensitive. The beekeeper went jack, happy anywhere else midnight certain now you're gonna get up and point out. He did seasons on malcolm and hated to see it go, but the shows cancellation turned out to be a very lucky moment. Had mouth em in the metal been picked up, I would not have been available. The pilot of breaking bad and right now someone else will be sitting in this chair. Talking to you not me, luck, both good and add figures, a lot and grants in life and in the memoir he's just written its published by Simon Schuster, which is owned by CBS. He grew up in a family it new first hand the uncertainty of life in show business. His parents were both actors, his or gave it up to raise Brian, his brother and sister, while his father struggled to make a name for himself in hollywood he read

We wanted to be a star. He really wanted a hit. Big observation goes number three: Emergency lab, but mostly Joe cranston got small parts in films like the beginning of the end, getting eaten, by giant grasshopper events lay his father realise that playing bit parts was about as far as he was going to go. There would be no start He had a massive middle age breakdown and left the family and then a just. lately fell apart and my mother was heartbroken just completely devastated to make ends meet. we started selling off all our possessions. Your poor we had Our house foreclosed on your kicked out. It was the nineteen sixty three

and Brian was eleven years old being from a divorced family, almost felt like scarlet letter at times, and I denied it for a long time. In fact, I told our dear friends the barrel boys five is live next door to us. Why are we not see your dad anymore? All we are he I lie. There said he home at night. When you guys your bed, he gets us out. We play. I said it so much. I started to believe it myself. The abandonment by his father cried did anger and resentment, but also a deep reservoir of life. Lessons and emotions that he would draw upon his. He grew older and decided to become an actor. The perils of stardom and the IMF Britain's of family. Thirty years ago, one of forgettable show called air wolf. He met other young actor. Who was unforgettable. Nothing has Robin s, oil rich kid who never had to pay for anything you. He was the man

guy and robins eared and was one of his hostage. He was an amazing after and one of the funniest people had ever met and took a while for you to get to go. Oh yeah we ran into each other like eight months later, and we kissed for like a second to. Let me demonstrate read a friend. This is the duration of the kiss. That's acceptable. I get to see you yeah. When you make a mistake and stay too long at the lips. This is this is how long, I hi hawaii it and that's what happened what was that, oh, it was just like the queue sealed the deal and they were made. He did nineteen eighty nine among the well wishers work, grandsons, mother and father keeping their distance from each other.

Looking and rob and had been married for twenty seven years now they still, in the same house where they raise their daughter and Brian still goes to work most every day This is where you're shooting the scene. This is where we're shooting a in we're in click on the set of sneaky pete. Let's get busy attend, pard crime drama grants than is doing for amazon. Prime. On the new frontier of original streaming- video- oh my god, he should more did into his scheduled between writing the book and making a couple of new movies. This is his baby and he's running the show doing four jobs at once check. So your co creator yeah the directing executive bursar actor. Yes, I do force myself to sleep with myself to get the job but as always in disappointment. What's really important this day, he's wearing his directors hat checking camera nausea and answering questions from the cast which includes Margo Morton Margo.

Take the blouse off and try this on now I'll go seafood, it's a busy time, but cranston wants to take advantage of every opportunity he has good fortune has brought him while his career is still hot. Do you really believe that there's going to be a time when people said no thanks? not anymore. I don't know you you do. Oh, it's cyclical! I'm writing a wave right now and I recognize it, but I want to do as much work as I can do the best I can. And when it's all said and done- and they say get out of the water you're done. I want so exhausted. That I look forward to it, I hope you're right, I don't have anything left in the tank. Everything we thought would be remiss if we ended this story without revealing the cramped and many fans. Some very personal, informed can he shared while discussing these two favorite character

how, on malcolm in the middle and Walter white, from breaking back big difference twin how walter like it's quite a bit of difference between, although tidy, why these were running think we're in common. That was a thing. I've thought about that for how it was that he was just a big boy, so the tidy, why these seem to make sense for walt the tidy whitish, also made sense, because they were pathetic. Pathetic sat mean you wear boxers. I'd do do boxes or nothing at all

I'm steve Croft will be back next week. For another edition of sixty minutes. Cbs fridays we may have been criminals seeking redemption. That's all we are now takes courage, we're firefighters, fire, kansas second chance from producer jerry, bruckheimer or save as many lives as possible. Tv's top new series, three, incidentally, the poor stained, someone else's life, the monitoring work, don't worry, let's go. We can do this country fridays on CBS and streaming on paramount.