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CLASSIC: The Placebo Effect

2020-09-08 | 🔗

The placebo effect is pretty freaky when you think about it: just believing that a harmless substance is a medicine can really produce measurable benefits. It sounds crazy, but the placebo effect is real, and its implications continue to fascinate scientists. So why does it appear to be getting stronger?

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This is an unofficial transcript meant for reference. Accuracy is not guaranteed.
If doctors, nurses and grocery store clerks can, where last for ten or twelve hours. If you were to ask for an hour or less when you go to the store, do your part mask of America was reared council support for this pod cast comes from Burma. Unprecedented risks are at play in this election. What will be the impact on rates spreads and effects from a change in the White House unpredictable times? Call for expert insights, listen to the pod cast falling into place. A corona session election by Margaret Currents, head of global, fixed income, currencies and commodities. Macro strategy get her expertise at B, M, o c m dot com, slash code that's be an oh see. Em doc harm slash covered macro strategy. We work here, so we dug this one out of the archives because we thought it was good fit in recent episode. We talked about faith healing and we mention the policy will affect them.
Kept talking about this placebo effect episode. We did remember. We really did and so the great opportunity, no time like the present, to go back and revisit this classic stuff. They don't want you to know from yesteryear on the placebo effect enjoy, from you- a phone to ghosts and government cover. Ups histories, riddled with unexplained events. You can turn back now or learn the stuff. They don't want you to know. Everybody welcome back to the show. My name is met, and I am then- and today we're gonna be talking about something that been doing since I was a we take something my mom taught me whenever I feel like I'm getting sick in ignoring the cold season right now, and I tend to get one nice bout of sickness every year and I have gotten the sickness ever since
I was a little boy and without my Mamma do is give me a giant glass of orange juice and she would say drink this it'll make you feel better and so now, even I know I'm thirty. Now, in this year I've been drinking. Would you like a madman- because I feel like it's gonna- stave off the sickness That's coming on. I know it's coming I've learned over the course of the past. Few months said this is The vitamin c is actually doing anything to my immune system. Ha ok, our belief that vitamins Really you are doing anything about that. Well, though, there probably still good for you, even if even it's true that you're not doing anything good for my body, but it has no direct effect. Would signal more extreme example. Do you have any mind. Anyone who has, as my did have asthma actuarial value grew out of there. I had women white boy syndrome. What the heck is
hoping that my wife is talk to me about, I don't know something about our genes, man. I got all these recessive genes in me. Allegedly, you know well why boys they tend to get a little sick, wise what's up to one of those machines, a respirator at night, really as a key area while well. Luckily, this, while you're not hampered those talking about in a novel that I really enjoyed was pretty creepy called it by Stephen King. There are. Some of you may have read it already, sure a lot of people have seen the many series we read the book? I hate to be that guy, but the book is crazy, good and scary and freaky anyhow in it. There is a character named Eddie cast Brac or something like that. Any k will call on Eddie.
Is a bit of a hypochondriac any as very overbearing, mother and eddies mother is convinced that Eddie has Asthma. Eddie himself is also convinced that he has asthma and There's a spoiler alert here and I feel like it start to not. Two crappy you say this is bit out for a while really breaking story, then breaking an outbreak in a huge plot point: the story, one thing that you find throughout the story is that eighty k doesn't have asthma and the entire time that he thought he didn't as a child. Here pharmacists was trying to placate his mother by giving him just an inhaler that had some stuff sprayed in it to give it a medicinal crappy taste and despite the fact that this was poor,
be much foul tasting water, a cured, eddies, imagined, asthma. Every time, ladies and gentlemen, why not now you are talking about today is the placebo affect and a placebo effect is not just something that allows a reported, ported medicine to fit say, psychological or psychosomatic disease. It can actually cure. Real conditions and from what we ve been learning. Never saw on this. Apparently the placebo effect is getting stronger. When you think that How is she crazy to me. So what we are really to about. Here is the power of the human brain in the mind and belief, the power of belief and this where it gets a little weird for me, because I have a hard time really grasping somebody,
stuff because seem so pseudo scientific. It seems almost almost spiritual and away where it kind of it bridges that mind body gap stuff for me to read my head around really but its fascinating, my god. It's fascinating! Why? If I give you a pill that will help you wrap your head around feebly. If that would probably worth I might have to be, for my doktor at least have the herself has been shown to be true, I will start digging into this ban. Ok, let's define it first, ok, ah the placebo effect according to rational way. Which we want to check out here, because we figured they would have the least aspect twice definition, so they it's a psychosomatic phenomenon in which symptoms of a disease or condition, lesson or even appear to be King George, completely from
the patient, being merely exposed to a treatment of this impasse, because it means symptoms might disappear. They might feel better. They might actually be better whether or not the treatment they giving had any real medicinal a factor or active chemical? pharmacological agent in there. That means The idea that you are somehow being treated can affect your your mind, such that your mind makes a fair on your body, yeah. Imagine yourself! Well, if so crazy ages, it's almost oh, it's allowing its allow you to unlock you're, your immune system than already exists within you to fight off whatever the thing is that you're trying to be right, and we know that we know that there are there.
Some measurable effects of the mental outlook The human body mind over matter. If you will write- and it's strange because you- and I didn't have episode soul back the we re released recently. Ask him whether or not the placebo effect this getting straw No. We dug into it with more details in this pie cast, and we have some interesting things to tell to tell you Lee Guys and Ladys out there today. But before we get to that lets, you say some weird. Maybe just being may be cool facts about the placebo effect, one, the packaging matters, air, the packaging on the pillow matters, if its flashy, it looks like they spend a lot of money, creating this package, which means Amy they spend a lot of money. Creating this pillar whenever this solution is that I'm taking that's crazy yeah, it's it's an effect
it also transcends medicine. People will judge wine. That seems to come in a more expensive model as a better. Why? Oh yeah, oh totally or in here's another weird thing. Then older drugs, the real drugs that actually have some kind of active agent in them. Don't seem to work as well anymore, because there older, in this, this is really where there are lots of things you can get into with this fact. But ok, so somebody's perception of it as less effective or because I've been around for a long time as this new drug. There is essentially the same thing and possibly even has the same. Active ingredient in it will be stroll have a stronger effect and there another thing: there's a huge debate between the medical community.
The respective little islands in the archipelago of medicine, theirs is huge debate about how alternative medicine quota or homeopathy works. Some people believe that its entirely due to the placebo effect than if you really believe you're drinking yield energized. Or were you, are having a Europe opera is aligned that the simple belief that a patient might have that this is working. Is the engine behind the results. Now, We're not doing an episode right now on an eternity of medicine, in or homeopathy here or any of that stuff? We will do an episode on it. You would like to hear it in the future interesting other facts about the placebo effect it has been observed in both animals and babies,
that, though the weird thing about that, then, is that it usually require some kind of conditioning which basically just mean someone telling you hey man, I'm giving you this pill and it's gonna help with your boss. I guess you have to know what is what the mechanism is not learned. Yes exactly, but but it showed the way in babies and animals who and how the hell do you translate for, let's see in Orca whale that this medicine that you're giving it as Gonna help with its fin, who no but orca whales are murdered Firstly, intelligent, it's true, so they might, they might have able to pick it up. Maybe murderously intelligent right, so we- said: pussy was more expense work, better I also know that if you, if you have more of a placebo, then you will feel like it's more effect.
You know just like when you're taking real medicine we'll take two pills, then it'll have an increased effect, a pair leader even works when the medicine is fake. So if you take to sugar pills- or a blue sky, cough medicine, doses or whatever ground. In a war it will have more of a dramatic placebo effect or has also shown that more the more dramatic the the way you get the medicine the way it's given to you, the better it's gonna work. So what so? If I just give you a pill that you have to take, have a certain effect, but if I roll up with a syringe and give you an injection of just some sailing, then you know that's! That's in that's an intensive thing that I have just given you rub it requires more directly and your bloodstream yeah, it's gonna, make you feel like I'm doing more in and is probably can work better. So we could also extend that
between the doctors. Talking with you. If the doktor said you down and says you Matthew, this is an astonishing new experimental treatment. This will cure you yeah, Then you'll be more likely to feel the effects raped me Arab, coming from a place of authority, in Vienna. We ve explored this before ban, but that authoritative voice of someone who seems at least seems to be an expert and something it that information comes off much more strongly. All you need is that subtitle at the bottom right expert, unanswered acts here. Yet we also know that policy those can overpower real pharmacological effects. So people, for instance, were given drug,
to induce nausea, didn't develop symptoms when they were told the treatment would actually wait for it. Relieved, nausea, that's! Why yeah. I just need. I just need to sit down for a second, then I think my my aunt. I nausea medication is working. It was. May nineteen nineteen eighty three in Springfield organ in the middle and otherwise peaceful cool spring night, a car arrived. Can't, you will admit Hospital, Diane Downs and hope. The children had been shot Charles Levin was dead and Danny Three and Christie ate her life threatening injuries A year later, Diane herself was found guilty for the shootings in the eightys there was a shocking headline story of fatal attraction, authorities believe Diane's in fact
situation with a married man who said He had no interest in being a father to anyone's children. Was the possible motive behind her shooting her three adds one year later, at her trial, she was pregnant that child was Becky Babcock for years. Becky has tried to come to terms with who were mother is, but one mystery has haunted her. Who is our biological father she's? What I call a jackpot match. Did you find Becky's biological father join me as search for the answer and explore Becky's and are mothers passed on this season of happy face present to face. Listen, anomaly, Iheart, radio, app apple podcast or wherever you find your favorite shows.
How did the world's greatest entrepreneurs find their way to such prominent positions of success? I'm Jefferson thought in the art of the hustle my podcast from my heart radio. I sit down a chat with shall innovators and magnates my friends? through my work as the co founder of summit, Gaslight, CO, founder of the boy lives matter, movement, Patrice Colors, former ceo of Twitter, Dick Castilla, leading global conservation scientists in some giant and thought leaders liked him fair, and Simon Cynic join us each week? We discuss successes failures. Son events and, of course, the insights and critical advice that All their lives are the hustle podcast created spire the entrepreneurs shaping our future. Listen to them of the hustle Iheart radio Apple pie
wherever you get your podcast vomit try not that we cannot skim over some of these sooner alot of facts that we will have to get get too by the press. Mary thing we want to talk about is that the placebo effect does appear to be getting stronger overtime. And some of this is due to the idea that our expectations of medicine, just what medicine treat, but what medicine is have changed over time. So here's the question that is opposed. But in fact becoming stronger, or are we measuring things differently? What wickets? That's an excellent question, so this goes. The Erika things are to be able to talk about here, but well, the most important one, I'm gonna we're gonna leave for the anchors. I think that's the most interesting, ok,
how about howl, how wide Measurements are ah below will go back to that later that when the most interesting so from two thousand to two thousand six: the number of drugs that were asked after face to clinical trials that that's the volunteer trials. Ok at airports college student trials exactly yes, increased by twenty percent, because the drugs couldn't be the placebos than they were being compared to which is wild its while men yeah and there there are also when we dug incidents. We found that there were a few big factors. Generated this appearance of an increase in the policy will affect the first one. One of the big keys is powerful advertising. And if you think about it right cause advertising affects the mind and the possible effect is a product of the mind and matter.
That again, is that mind body connection that it so fasting we're gonna have to have some kind of large serious just on this ban. Just on the mind body connection and No need to do. We need to get ready to get people from stuff a boy your mind. Oh yeah, ethical, what we should do, maybe you and Robert and Julian I can all take a vision classed so the the The interesting thing here is that, for anyone who doesn't know the at least a Western pharmaceutical industry, which is the vast majority of the international pharmaceutical industry, spin so much money on advertising. Now you would think that people spend so much more money on research and design. How can we Cure HIV. How can we cure insert disease here where I live.
So more of my drug right, a lot of his more. How can we actually get people to take more sir tack yet and not only sell it monetarily but sell it to you that it works that it's a real thing, that is functioning ineffective, and this goes. Something else that I want to talk about- nowhere, saving the big one for the end. What now? the reason for the increase in the perception of the placebo effect is that we have a much larger pool. Of diseases, now and psychological disorders have begun to be counted as something euro. So are you depressed now you You're here you have, oh, of some sort. You uneasy hd, you, for instance in in various things, are women
qualified as psychological disorders rather than physical, disordered, asleep. So well, sometimes you feel guilty you should take. This Look at this q animation tat we ve created for it, see Paley and you know the fine print about these terrible side effects in the weird dreams? Oh yeah me, cause livid, hallucinations, strange dreams, side irritation whatever that yeah well now, of course, we're not saying two in any way denigrate people who do suffer from Cyclops disorders and we're not saying absolutely not we're not saying that this that the medicine that these people may be taking his rule, real What we are saying is that the placebo effect is terrible in these psychological Disorders is well and It is no secret that cycle Google disorders are widely mistake
so yes, I've had many conversations with my wife, the school psychologist about diagnosis, especially in younger people, read someone is. We you know that Have you ever of a young human being here, can seem erratic in comparison to an older human being different disorders, manifest at different times there are a lot of factors play its cut and thing. So pharmaceutical companies have and a lot of money searching these diseases specifically right. Oh yeah, absolutely, and just another thing here, ban that come it struck me as crazy as at the attitude of the the a doktor comes at your disease and the way they basically weather. Whether or not they give you a negative or positive diagnosis, initially is gonna change. Can change?
it's the way at the outcome of whatever it is that you were suffering from ok, so just weather not. You have a positive or negative outlook mine whatever it is that you're going through can change the way effectually, ok, so ever doktor comes in and says you know, I've got great news: is Mr Bowling. Your hammer, too, will be completely solved by this operation that were do oh, not operation. That's important! Us all lie this pill, the earth, or even better this injection right, verses. We ve got terrible news Mr Bowling there's only one hope, fear a hammer tell if this amputate a placebo, when the ice. Now it's time for Thee largest reason, maybe what,
the Drum Roll and then that the honour is yours. So the most interesting reason that it seems the placebo effect is increasing, is because our our range, our scope, is getting much larger and were really yet many more developing nations and getting day from developing nations that have access to drugs that they have never really had access to before? Ok in its western medicine land? There's, there's kind of this. This thought that for medicine is very powerful and the belief in this medicine itself is very strong in a lot of developing nations. So when you If someone in it
solving nation, a let's say, a handful of pills. Then you say this is going to cure acts. Were you the strengthened that belief of that medicine, even if it's a placebo, is so great that it seems to be almost larger there? Also, the ex, backed and see, which is key. In in the effect of a placebo, means that placebos in developing or poor countries actually do better than that wooden in a developed country yeah, it's free pretty weird, is a yes and so We must go prices since the as you have seen since we're measuring from a much larger sample size, yes, we're bringing up the average yes and I shall we be remiss if we didn't pointed out a lot not a lot, but some of those conspiracy theories about the way that
Pharmaceutical corporations handle experimental trials Developing countries have a grain of truth to them, as you have asked, a few of them are absolutely true, so there is. There is a well of information that we can examine their in a larger context. And there's a lot here that we're not touching too much about the the problem some organised medicine. The way it's organised does the EIA. More harm than good? That's one that we hear brought up a lot here and, I don't know why you man but I'd love to examine those in the future and hear what our listeners think about this, but first before we tell you how to contact us, let's hit one last thing been: ok, what's up? Let's talk about the power of belief and its limitations through good, yes, sort of
The future the going forward was effect. Now we ve explained a couple of reasons why the method, dollars you you're the sample size may have changed to effect, the police either. We also talked about the expectation medicine and disorders, are now assigned to talk about how we can you this information, you me everybody listening to, ah to bring forth, hopefully fruitful changes. We have men. Yes, he hears the here's the thing in some cases, even if you know you're taking a placebo, affect it still seems to have an effect. That's that's pretty. Crazy right. So, even if you are aware that you are just taking a sugar pill, you can convince yourself that it's not just the sugar pill and it may help you. Yes, that's true
so what are we seeing as it may be possible to construct psychological strategies that hack, a patient I too, to exploit the placebo effect for positive results. Now are better results rather now. We know, of course, that, If someone is, for instance, horrifically burned, you can't give them a sugar pill and solve their problems, absolutely not their their devil limits to this. If the word, then, everybody would just live forever written what we we do know that there is we're a pioneering age of exploration between the relationship between the human mind, that the human body and the placebo effect is much more likely to be the tip of an iceberg than it is the iceberg. Entire So, although we know why its increasing we do know that there's something.
To his reminded me of a lot of other sort of placebo effect related things about the mind having power over the body but before I get on a rat for it for too long? We have already built up our case, for pharmaceutical shenanigans. In the developed world which we will return to and we ve already touched on some of the conspiratorial things that people say about alternative medicine, verses, western medicine, and we want to hear what you think about it, because all of us, ass ideas come directly from you the listener and prove that Do some listener: Male Matt. What do you say? Absolute Let's get started with Kelly M, she wrote to us Said: hey guys, I'm really enjoying your podcast so far you sometimes
concerning the episode is running too long, but in my opinion the episodes are too short. Your car stations are really engaging, and I want to hear more details and nuances about each topic. Keep up the good work Kelly, while life. Bad were reading that at the end of her we'll Kelly. Thank you so much for writing and we really appreciate your input and you know sometimes the the I'm constraints we just put em on our ourselves because we cannot have to get in and out here quickly other summit, people using this this recording studio. But you know what I think we can make time was. What we can do in some cases they may be a little longer and other cases made they may be a little shorter, but hopefully you'll enjoy them yet one interesting thing Kelly they might want to know. Is that all of our podcast surprise about an hour and a half will afford them and they heavily were directed Aims,
no kidding I'm kidding. We do. We are really excited to have a longer show opportunity. We're gonna see out how much we can didn't you. The audio episodes before the powers that be catches down in tears here. So in the meantime, as we build this crazy house of cards in a windy room, I wish you luck with the next level. Let us know what you think do please find us on Facebook and become our friend on Facebook. We would really appreciate it makes us much less likely to be fired, if you say hey, Facebook is for the birds, whatever that's dumb, while speaking birds. Why not try whether we are on there too. We are conspiracy, stuff at both of these and and that's the end of this classic so, if you have any thoughts or questions about this episode, you can get into contact with us in an or of different ways. One of the best is taken
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Transcript generated on 2020-09-08.