Audible, sponsor of the audible audio pioneer awarded this year's Iheart radio podcast towards is the best way to stay informed, inspired and entertained. Discover the world's largest selection of audio titles anytime anywhere, with the audible at whether you want to tackle a new skill. Focus on your healthy self. Where discover new releases, there's no better placed to listen, then audible, start your free thirty day, audible trial. Today in your first audio book, is on us visit, audible, dot com, slash as Y S, K or text. As well as key to five hundred five hundred hey. Everyone were coming to SALT Lake City Utah in Phoenix Arizona. This fall yeah October, twenty third, we're gonna, be it SALT Lake City, Graham Theater, and then the next night October. Twenty fourth will be in Phoenix an we added. A second show to her Melbourne, show right, that's right, a second

your show in Melbourne, so you can get all the information for all of these shows it s. Why ask a live dot com! Welcome to stop! You should now friend asked her for Stockholm Hay and welcome it. I guess I've Josh Clark. There's Charles, I reach a bright there's jerry over there, and here we are doing maybe we're gonna be the best episode of stuff you should know we ve ever really stairs back you're welcome back to front hospice. She said she just through her. Her can of carbonated wandered down in belts,

I was gonna name jacket, but I'm glad you didn't man, we do enough buzz marketing incident seriously. We can never do enough in the agri saw you feeling, ok, yeah. I feel like this articles ticked me off there. It is it's not that that fraud Rick, who is here this is the only Phd House of works. Ever it was. He didn't do anything wrong like the logic behind the copy lay out is what does it? It is almost like designed to keep from sticking in your mind, the information you reading he s like it's like if we pursue in a grocery store put the milk together with, like the can spinach in an idle, unexpected people, real women find it. I I have you ever they met at the trees, puffs gay, and really the cheese plus a cash use.

Ass little making mile. I can do this by the end of the episode I'll have it, but the point is: is it this about the oatmeal with pickled herring? Ok, it's twenty that you were picking. Things are still missing. I know my imagination died aged ten at the edges slaughter I turn into about that. I thought it was a pretty dry article. There. There was like none of the character of house the forks articles. If it read like a medical journal from the nineteen fifty diabetes, how to out again, like boy work, how we can make this one? Well, that's our job so get started, making us find her yet about some stats. I know it just says the activities are pretty outdated. Yeah. I saw the two it's gum way worsens Coal is red. Has it in that we're talking about in the United States, but in the last twenty years type two diabetes has tripled.

Eighty four million Americans now have pre diabetes and ninety percent dont know yeah. That's startling, yeah wolf we'll get into predictable in a minute and about thirty million people currently have diabetes in America, title tied to or total I think, total hooker at a total cost of including met. Last wages are three hundred and twenty seven billion dollars a year a year in the United States alone. I saw work, wide something like four hundred million people have diabetes and American picks up how many others thirty. The ok which is suppressed. Because it didn't used to be that way. It used to be like a wealthy western disease and all of a sudden is starting to spread throughout the world, which is really kind of shocking and jarring like this is a huge

Greece in this year's has become a really big problem for not just like healthcare in hours, but you know the people with diabetes to there Buying from it, so during a million and a half deaths a year in the world, yet it's a seventh leading cause of death in United States right now, in its here's, the thing it's the type two diabetes is from what we understand utterly preventable. It looks like it is utterly preventable from one from what I've seen, not one single person who has type two diabetes has haven't like they were genetically destined to have it. Although there is some other evidence, I will talk about that suggests otherwise berwin and give anything up yeah, but I mean we can pretty much say now that it is let's just go and say largely caused by

being out of shape in being overweight and eating like terrible stuff. I am time I love this article Chuck because it's one of those ones where it's like of all of this makes total sense. Like I love the body just like I love her sciences near its just, we can kind of it forms a system that we can understand and like when you understand this. One part you're, like all the other part that happens, makes total sense. That's diabetes, yeah hit the body neurosciences. I like mysticism, cosmology deadlocks boy. Why did we did it chauvelin?

I was thinking when the other data we did jackhammers, no is even even worse than that. I can remember us like a wider grieve in its hand. Back occasionally, look there, the old, less from repeating, selects and NGO were few of them myself, it's weird right, so we need to break down. Her did mean that point, but a breaking down in this in this show you note of its cheerier, and that was sort of. Indeed, there was a foreshadowing pine how it was, but we do need to break down the whole spiel with glucose, yeah and insulin cause as the root of all its a disorder of glucose. Yet, as a matter of is yeah disorder both

yeah they're, if either high or low or or none yeah. So I'll get us talk about glucose first, I well before even talk about glucose. We need to define what a simple sugar is or a simple carbohydrate. It can be called. These are carbs at her absorb very quickly for energy and their called simple Kazi only have one or two units of sugar, as opposed to like a complex carbohydrate right in glucose is a simple sugar rice and his senses, a simple sugar. I think that means it can be broken up. Different types of complex sugars, so not just like sugar, but carbs, like you, said, right yeah. This is the sugar that gives all the cells in your body energy. To do so. Silly thing great enters the bloodstream through

intestine all the cellular Gimme some sugar baby yeah. This comes from the foot for food for the two: it it really that's right, sir. You eat some food particularly say a carbohydrate rich food and your gut start to break it down and it breaks down ultimately to that glucose the simplest form of sugar that the body can use for energy without being stripped down further and ex shoots out through the bloodstream, and it's just a free for all right cells. Sure, like you, said use. Stuff in some cells in particular use nothing but glucose, some use glucose and, like other stuff like ATP here, which are those red blood cells, in cells. Quite important Leah use nothing but glucose for energy, so glucose is extraordinarily important. Yeah in which her body wants to do. We always talk about that. Homeostasis is another example that your body wants to keep a constant glucose supply for yourselves. We don't want it to be super high or too low.

It does this in a pretty interesting way. Otherwise, when we like right after we would be great and then, if we did aid for awhile or went to sleep at night we die potentially or his mission, we slept long enough because again, this is the stuff that fuels yourselves. Yourselves need fuel twenty four hours a day that doesn't care, whether you sleeping or not, right. That would solve everything. If yourselves went to sleep it would, when you slept they just stop YAP and for once now they're always talk talk, talk, always we're moving, which actually, I guess, is good. Because again, if you sell stopped working, then you die right. Ok, so that's glucose energy, that power cells, some cells exclusively in your body- wants to keep a nice constantly. Yet then you get it through. Food which could conceivably Spyker glucose so right when you eat something and always a new ever a surplus of glucose. Rather than that, even keel. Homeostasis glucose in your bloodstream

your body has a way of dealing with this, and it's called insulin and insulin is one of two chemicals that are made by the pancreatic islets I facility, I was, I don't know, did you look up, I think his eyelids, like islands like a measly tiny islands, it's probably there there. Tiny islands is organ com. From now on cause, I don't want to get it wrong for the rest of the episode, but they're they're called tiny owns because their indeed little endocrine cells inside your pancreas. So they're they're, embedded like a journalist with a troop detachment. Basically, yes, your pancreas in and in this case, is producing too insulin and like a gone, I'm sorry

look again glucose gone, looking honour, alpha cells are produced by ourselves and secreted by ourselves. Insulin are the beta cells all of its produced in the pancreas like he said that with visible islands, but so is focused

here's a better one than than a military analogy, a post office in an airport. It's like here we're going to serve you, our customers, we're just gonna go to you did they have as yet someday- and this is one of the terrain only report either. Is why why's he so who thought that was gonna come up, so you ve got these little cells that are specialised to create insulin, to release insulin from the liver or no from the pancreas. I'm sorry in response to glucose becoming abundant in your got as your digesting. Your gut sends out signal, saying: hey get a bunch of glucose here. You guys want to do something and the beta cell say were on it and start releasing insolent, so insolent enters the bloodstream and its whole jam.

Is to take the glucose that enters the bloodstream and give it to cells, and it doesn't just push it down the cells throats. Apparently, the cells have some sort of saying whether they accept glucose you're, not sure, but the only the only person, they're gonna eggs have glucose from his insulin. So insulin will take this glucose two different types of cells and with different cells. Different things happen to yeah like it depends on what party or body if you're the liver or muscle cells is gonna, store that glucose and something called Gleich again, yes, like just chains of glucose right yeah, it's gonna stimulate that sells to form fats from Yes, it's english role than the liver and muscle cells is gonna. Make those make proteins from amino yeah- and these are like a three base- protein or based nutrients- that you get from eating food right, no acids, Fettes fatty acids and glucose of and then your body makes use of those because insulin deliver.

Resumed cells around the body yet and it's gonna inhibit delivering kidney cells for making glucose, and this is something called glucose, NEO Genesis, which is confused me just a little bit. But why because it just found out something about the metabolic pathway like I fully grasped, think what it is that maybe my answers? Just I'm not smart enough to get. I don't think that's at all, if it weren't for you to do anything to prom. If anything, it was the article check. Not you will know this articles, police thinking, but they also went to kids hell. Sites like out is there, but it makes sense in that like if you will die if you dont have the sources of energy yeah you're gonna have some backup plan and the backup plan is while we probably have some constituent parts that we can put together to make her own glucose. So that's like plan B B is make your own glucose.

In its glucose NEO Genesis. Ok, that's what I think I mean that's my interpretation Geneva and I play a doctor on tv. Doktor Drake remark yourself about those friends. You probably much friends did you. I saw an episode or to I love that they were you indifference. Oh yeah man still am yeah. I watch this reruns orally, yet twenty three dated show now: oh man clothed hairs, the wider evil yeah I mean everything about it that they hung out at a coffee shop. When I was new year gas, if you gas, it showed a day, would look like a Benetton Colors adventure, and rightly so. Progress are eight so that, at the end of the day, though, insulin is gonna store nutrients right after that meal. But by reducing these concentrations of glucose and, like you said, the fatty acids and amino acids, those three main components right

which is pretty interesting, as you really only hear of insulin dealing with blood sugar, but it deals with the main three nutrients. I didn't know that before did you, I don't think I do. It's it's a pretty handy little hormones, and by the way it's a protein hormone. Glucose gets all the headlines. It does because it's the maker and will see what happens when insulin can't do its job. What you It is dire bees in the symptoms of diabetes. We'll talk about that later. But first, let's talk about glucose gone. I thought you said for second, the simpsons of diabetes. The symptoms began, the who have diabetes, uncensored, o, probably homer and Wigan yeah. I guess in Barney sure don't move that will become clear, as we explained diabetes more right, both over glue, Gambro, quick, because you ve got insulin, doing its thing and it's pretty clear. Now what insulin does but there's another hormone that does the exact opposite that comes from those pancreatic,

tiny islands to hear this, I thought was pretty need. As far as that homey stasis, the body has like two methods to deal with a slight yep. So, like you said, if you, go without eating or you sleep. If yourselves don't get that glucose that they need they starve and die So why you're sleeping and not eating your yourselves are still power still need their energy. So body, has away to deal with this and it is by producing glucose glucose gin right. And the a little confusing cause it's glucose gone and Glucose Jan oh yeah, I'm both with the De Luca gone, is what I'm talking about. Ok, that's how you body deals with the lack of a flood of new glucose being introduced from food that right and that comes from the alpha cells, angry Eric, I right yeah and it acts on those same cells, but it just says the opposite effect, which is pretty cool like in the end it's gonna like when you

sleeping and when you're not eating. It's gonna mobilise glucose and where'd stored up here they and say hey. We need the stuff now right, so it goes to the never sell and muscles in the muscles and says: hey you, member, the the glue kitchen in there with a chain of its called. Yes, like a giant, so the the glucose gone goes to the liver cells and the muscle cells right there, and it says, hey. You remember the chain of glucose that you made the Gleich origin the other day. Well, we need it yes and so break it up in

Did it out to me in all just get it into bloodstream, and it does that to deliver and muscle cells. It also tells the kidneys and liver is by the way liver. While here, why don't you kick awesome glucose NEO Genesis to make some glucose right, and so all of a sudden, the low blood sugar in your bloodstream comes up to normal and yourselves all say who re were saved in insolent, Giza lifted up on everybody's shoulders and all the cells carried around four triumphant fish shaking parade yeah is pretty great cause. This is all happening where sleeping this is war not eating right? So all this, this is how you, your body, keeps homeostasis for your blood sugar in your bloodstream, yourselves power. If you're healthy right, if this goes wrong, well, we'll find

are all about that right. After these messages des New year's resolutions are very, very difficult to keep getting. Exercise save more money. What have on this? We have a resolution that you can really work with stop wasting time going to the post office that right, you stamps dot com instead because they bring all the services of the. U S: postal service, right to your computer, with your small business, sinning invoice. Is or packages or an online seller shipping out products stamps that can handle it all with ease yet and get this with Sampson com. You get five cents off every first class stamp in up to forty percent of priority mail. This right? U S, postage twenty four, seven for any letter, any package, any class anywhere you want to send it, there's no risk and using our promo code, ass white, ass, gay you're gonna get this.

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or five million alarm. Yeah, nay. You know you d get this tested. They have little strips rican, put yourself in the finger and bleed on the strip yeah. So this is apparently the most complex thing of since the breath. Iser you a glue glucose call tolerance test with that. I'm sorry, I guess that's it, a good glucose meter, you prick yourself and bleed under that little strip of paper, like you were saying that the blood reacts with a chemical. Or with an enzyme, I'm sorry on the strip, it's called glucose, oxidation and so, creates an entirely new compound glucose aid. Combined with another chemical, and that turns the Strip Blue right. Yes, and so you would think ok well, if it's blue it SAM! It's it's

I'm diabetic horror I'm in trouble. It is not only on fight now what the with the diabetes testing apparatus think us, with their called, does analyzes the shade of blue that that turned red zag, that's complicated at that may be the best blue, really Navy sure said, good second desire to please right but maybe be pretty cool. If that's how I did like all like is Robins, that's navy. Racket is a civilian and it made a local chirpy, sound civilian you're in trouble, while ass they used to test it, though, in fact, that the full name for diabetes is diabetes. Miletus Emmy, allied to U S than that literally means sweet urine, because in ancient times the test involved, the physician drinking your urine and going tat sweet you're in trouble, you're in trouble, you're in trouble,

So if you say that you have that sweet, diabetes, Miletus you're saying you got that sweet, sweet urine You know I rodya back in the day when I was writing speck script when I was in a way I wrote a seventy show: oh yeah, and was a Halloween episode where Eric PETE his pants at a haunted house in the title, the absurd was yearned for a treat. Oh, that's great man. I thought that was enough. Like man gonna see that once it meagre published those a b. I should take that up. Surely I mean I have like a digital copy? It have the literally find the paper take how many pages you think. I think it was like twenty four to thirty perfect

Take a photo of each play, a hundred navy, how I didn't like it. It's a posted on Instagram a page day for a month. People go crazy for air. Would love that? That's probably one of the better things ever wrote ogre out there like it was a legit. Seventy sharpest ever tell you about the Simpsons gripped arrow. Not enough about now get it through. Remember the one where it turns out that principle, skinners actually arm attains area, an area as well the great episodes. This one is: oh, if you, if you remember, unites, met greening most hated episodes. He hated that up his love that when I didn't know that at the time, because I wrote the sun speck to hoping that he'd notice it, although I never said it, but the at the end of that episode, they they judge says that it's a! U there you're never allowed to speak of this party.

I emphasise- starts with one of Armenians, Arians old friends coming to Springfield the start as life, a new strategy and he sees principle- skaters, hey Army are retains areas and all of a sudden, the police around in here our retains areas and all of a sudden, the police around in he's, taken away to jail and held, and it gets out, he escapes I think, gets out, and then Clinton was president when I wrote that he gets out somehow it gets silly Clinton that this town is like holding people hostage. Basically unconstitutionally, so Springfield gets invaded, I think it was like appropriately we'll ask link yeah, I think so. Actually I imagine a different life where I wrote for the seventy show that seventy show in Europe for the citizens and we like eight lunch together on the fox lot. Can I d be pretty caught me? How can I tell you something I am sure I would. I prefer this area. Yes, I prefer, while we do as someone who has never written for them,

I prefer, while we do as someone who has never written for the Simpsons, he had arrived refer the semantic I've been the writers room before I know it looks like a chain under the desk. I like it, we get too. We want to live in a way tat. I like ally, I've noticed our friends from New York or start in a mood Ella. Have you noticed that to get a hemorrhaging to get back to debate its, we should probably just said it all out now I think that's a nice change it and keep our eight. So in the case of diabetes, like we said it is why we are so what it was, but there are three types type one type to injustice: diabetes type. One is by far the in the minority its. It says here, five to ten percent, but I saw my kind of a straight up. Five percent number for the number of diabetes cases. Overall, ok, but they say five to ten percent, this article or it's called juvenile diabetes or insulin dependent.

When either not this is caused by a lack of insulin, either not much and times no insulin at all in their blood, and this is this is clearly genetic right says. An also could be our mental but yeah. They think it's possible possible that is caused by a virus closure to a virus, early childhood interests, deck back It's often auto immune reaction, and so your immune system attacks your beta cells, that produce insulin so destroys on air, and so you don't produce insulin and it happens in your younger years, maybe be adolescence, whereas wise called juvenile diabetes and you when you have type wine or juvenile diabetes You are you're dealing with it for life and we'll talk about her

You know managing entreating diabetes, but there's no cure for diabetes, but the idea that it's possible that this is the result of a virus has made some people call for research into a type one diabetes vaccine. How interesting which we just change everything for some people get because I mean like I don't like AIDS is certainly not a guy. You get what you deserve kind of thing, with type two diabetes but type one diabetes main you got zero say in this whatsoever, yeah so type to is the one that's most prevalent between ninety ninety five percent, adult onset diabetes. That is when You are usually over forty, usually between fifty and sixty, even I'm so you are usually overweight. Why are you nervous? I'm just nervous summoning happy end up type, two diabetes quality. I thought you might you're gonna say something wrong. Now, I'm nervous you nervous about diabetes. You hear it sounds like its virtually

destined that we're going. Yet I don't think it's in my family, but I'm overweight and forty, seven years old yeah. Need to get my act together like now. Yes in a like me. I wait another five or six years and inaccurate and there's no reason for us to lake. Just put it off until the end we can say like you can you can reverse pre diabetes, who diet and her. If you dont, even if you happy diabetes, you can witches you have higher than normal bludgeoners will see, but you don't well blown diabetes yet, and you can actually reverse coarsely s not too late doing something like what you're talking I now be very high in its great. This is a wake up. Call like your body literally, can inch up to that line and if you do the right It can go well all right, yeah I'll back off then I like, the way you're going, Gimme, smaller, sorry, baby, get on that Palatine Jug, the reverse, mark your mother in advertising with us. Are they still

will they were, and I still have that thing- I love it. It's nice! I just need to love every day right, not like. I love it. Every couple of weeks, crusher hell, you know anyway. Type to like I said, is about ninety. Ninety. Five percent in this is when you have higher insolent in your blood, not lower like the case of type one right, because you have a lot of insulin. It's just not working, which is wide type. Two diabetes is also key insulin, resistance, diabetes! Is that right, non insulin, dependent, okay, more insolent resistant, yeah, ok, yeah! So damn say you're bodies producing insulin, just fine, but first reason or another, and this seems to be the mystery at the heart of diabetes? Yourselves, don't respond, insolent anymore, they won't say. Oh, it's insulin, sure bring me some glucose alternate into a chain of of glucose bear a date or no exact

Why right I mean felt her. That's all I'm saying that's that's. Why mystery at the heart of diabetes? They don't know what the problem is, with insolent think figure that I think that they could actually cure diabetes right instead, what they ve learned to two cures, some of the problems associated with it right witches, but they did deftly notes for sure linked to obesity,

Yes, they do so that's type, two, we'll talk a little more about how that actually works is farmers in of the the effects that it has on your your body, but one that some other research I found was that there is some evidence that it's possible that type two diabetes. The actual mechanism of it is the result of folded, Miss folded, proteins. So the same type of thing is like mad cow disease, her Kourou, they re for meeting like brains with some sort of spongiform disease. Right, remember that we talked about that vaguely, so they think that it's possible that type two diabetes is the same thing: Miss folded, protein and the third one, a kind of relates to type two diabetes. It seems as well gestation diabetes.

Yeah. This is, if you are pregnant woman, you can have acquire a guess: gestation Diabetes, the Good NEWS it usually will go away after babies delivered, but it can put risk for type to later, on your more at risk, if you're overtime, five having a baby, if you have a baby over have had a baby over nine pounds. Oh yeah If you are overweight, family history of it or if you are african american Hispanic Letty or native american Native American Pacific, I wonder- and I believe that's it- ok so which is interesting. It really is. I didn't see anywhere why they thought that I think really they attend different ethnicities

yeah why they would be at a higher risk than now. So I think that I get the impression Chuck for that. There's been like the American Diabetes Association has been around for a while and I stuff, and I ve been trying to do what they can, but then this in this enormous spike in be these cases in the west end. Now the world has really kind of drawn attention and funding to it and were now really diving into figure out what's going on, but we haven't figured it out yet, which is where we are now right of I'm sorry, one more thing: gestation of diabetes, they think, can actually be passed down. His type two diabetes to the spring interesting, that's yeah! Well! Yet so we're just learning about all this stuff now or it's a simple

wise for all three versions and types of diabetes Polly. Why should I say that when I can t say, you're very thirsty, Polly dips here you mean your very thirsty. You urinate a lot if your ways hungry if, but you are also losing weight for then you can explain that guided know that part about diabetes but never understand, diabetes and make sense glucose and the urine that sweet, sweet taste of urine fatigue lot. Tired, blurred vision, specifically changes in your vision. I'm numb, hands and feet fear to observe slow healing wounds and then abnormally high frequency of infection rack. So that's over those are the symptoms and, though, make sense ones. We explain what's going on

behind every year. But in some of these symptoms, though, in fact a lot of these symptoms can be other things too, which is why it's sort of distressing to be doing research? this and be like? Will wait a minute my I need glasses to read now but diabetes is over forty, I'm tired, like that also happens when you have a three year old diabetes. I have a lot of low healing source. Now, I'm just getting my photos disabling payment, because I have no sympathy. I do. I get numbness in my hands and feet. Sometimes I sleep, but that's been happening since by early thirties here and there, and that just could, because Europe, you sleep with my arm up and stuff like that, so you know I'm reading stuff animal. Regan out, go to the doctor. No, I do in last summer went there. My blood sugar was fine. When I go every march, oh you get accepted and get this far.

I didn't either I've been going every year and then skip this year. No were about to think we just found a new doktor who special houses in diabetes, I'm so nervous. Unlike his shoe, she one of those Who, like is like a hammer? everything looks like a nail schematic. You have died, It is only a trick myself in actually thinking it. Yeah did the dumping this. Here which was Gees again gain last year, like I am take your and get back and she hit this, which is the opposite of what you should do, but I was like I can't face my dockworkers when I go in there he's like what are you doing? Do he's very just matter of fact about everything to equity. Doing you gonna be one was old guys with diabetes right. He's around he'll, say that stuff to me- and I know it's a good. Well, you know it's up to you, it's good. To hear that I mean the you need that kind of straight talk from a doctor. You know they say or I've read that

weighing yourself every week, if you, if you're trying to lose weight, is bad. No, it's good, or I should say I way myself slowdowns a week. I see some, you shouldn't that's too much! Really! Yes, because your weight fluctuate so randomly throughout the week. I could show you can make moralize you want to do it once a week. At the same time, usually right after you get up now say morning, every week in you will see, going up or down you really be able to see four times a week. It is like all over the place. It doesn't make any sense. Yes did you can't make heads or tails of it once a week at the same time? That makes sense- and it has this logical, effective being like. Why don't wanna? I don't want to see a go up, so I'm I'm, I'm gonna, I'm not gonna. Let you like it either chocolate cigar. No, you have to say Oh yeah, I, like I said away myself too much, but I'll kick agenda once a week. I remember you will have. Thank you thanks for thanks for I should we take a break his

This episode still going on, I think so than your. I will be right back Let me tell you about people who love talking and always wanted. In the end, a chill PETE flayed, since he was three and big. His mom to let him stay on the ice. Why some nights he even slept in his happy skates PETE practiced in practice to one day when he was forty. Seven feet realized. He just wasn't that good, so he threw his gates in the trash. But then he heard how Geico proud partner of any Joe could save him money on car insurance. So he switched and saved a bunch. So it all worked out.

Chuck yeah, now we get to the point of the article. That's called: let's try and confuse people as much as possible. This is where the grocery store start, putting weird stuff next other stuff and expect you to just pretend like everything's normal, I tried to just mark the relevant parts to make it all makes sense and streamline it, and it still was confusing. Ok allow me great, thereby just correct my knuckles. That means it's. Each turned his terror accords prepare, prepare further monotony ready the honest droning right, which is basically how does this out as a lack of insulin, affect your body by Josh clerk? Yes, so always take different ones right. You ve got blood, well see here. Here's a good example: you got glucose appearing in year, urine above urinating frequently, but logically

glucose appearing in Europe, should follow after it and be in the same thing. So we're going to start with you urinate frequently Polly Gipsy, I think, is what are no Polly. Syria is what it's called right policy area, so That's just means you p alot way more than you normally would. If you didn't have diabetes- and this is actually easily explained right. You ve got a lot of glucose in your kidneys. Yes, because it's in your bloodstream and your kidneys, her ear the filter, one of the main filters for your body, yes, and so when you have liquid waste, it goes to the kidneys and in that liquid waste is a lot more glucose in your kiddies are used to processing, and so they become overloaded. There's like a backup of glucose, yet pretty simple, easy pc sensors. A backup other stuff, the actual

the actual thing that shoots urine off two year, urethra right, the Tribune Luman it it becomes backed up with glucose as well, because glucose retains water right means the to be a luminous says. I should probably gets rid of some of his army to start paying ceased being more and more right. Ok, that's one effect of it. That will also help make you thirsty, which is another some that's another. It's like a vicious cycle right, so you start drinking more and that is another symptom. So you drinking more but you're just being more because there's so much glucose in your blood. Now, because there's more glucose in your blood and your peering out more water from your bloodstream than usual, your blood actually becomes a little thicker. Yes, and you also Sodium, ok, right, so you're peeing a lot more you're drinking a lot more, but you just being a right out your blood's becoming thicker, so your boss, as war something's little off. I need some water coming dehydrated. Sending out this thirst signal. Isn't working, I mean a steel. So

order from the organs right. They actually become dehydrated. But the problem is: it does not solve the problem because are still, though they glucose, overloading you're kidding. You just p that water out. So again your constantly thirsty, there's a glucose that appears in your p, which is how ancient doctors said: yeah you ve got the diabetes and you you're mere organs are dehydrated, which is a bad jam. Deanna think they like in the thick and blood to like a molasses consistency right, not good. This article is in touch on it, but that leads to another thing: that's usually com or often co. Morbid with diabetes, is hypertension high blood pressure. Because your beer, your heart, is requiring more energy to pump his blood is a thicker and it's actually

hard on your blood cells as well, and that can lead to all sorts of things from cardiac arrest a stroke. So you can get all those in addition to diabetes just from having fix sweet blood, that's right! Molasses, blood dickens. Suite is usually good yet, but not in this case, maybe if it's in the syrup that you're either That will eventually give you diabetes. It's good are nowhere. Does it put us we're going back up to the top yeah, which we should a purchase, paying confusing people along with this article around so The whole reason you have high blood glucose levels is because your boss, He is not responding to insulin right right so because The insulin is running round going guys guys. What would I do what's the problem? Take this glucose in the cells just turn their back on the insulin and the influence is sad. You have a lot of insulin in your bloodstream, it's not doing anything, and so there, some other,

or secondary alarms, though your body sets off we got a lot of, we got a lot insulin and the bloodstream, but are so you're getting an energy there starving. So we need to start producing our own glucose right and that's where the glucose gone. The alpha cell secrete that LUCA gone and those levels rise in your bloodstream that acts on your liver and muscles liquid about to break down that Gleich again and releases while too much glucose into the blood. In that case, right, which is one reason why you suddenly lose weight inexplicably, despite eating all the time or being hungry Alla time here, because as far as your bodies concerned it, it's all its pretend, like your body, can't tell that there is a problem with the insulin all it noses that the cells are starving. Yes,

it's it's like its lack, some sort of gay irrigation, yet his show how much how much blood sugar there actually is in the bloodstream or how much insulin there is and that there is something wrong: its nose, the cells or starving. So it kicks off this thing where it makes its own glucose witches raises the levels even further and exacerbates the problem right. Ok, so your constantly hungry, because your body thinks yourselves are starving, but you start to lose weight despite eating, because it's also attacking those stores of glass kitchen. Does glucose chains and you're just you start losing weight just by eating a lot if you're, tired? That was another one of the symptoms because you're not absorbing that glucose? So it's not done everything burn for energy your hands and feet. Remember I talked about them.

Feeling number cold ass, because it increases asthmatic pressure of your blood that draws the water from your tissues. That means yourselves becomes everything becomes dehydrated and again that goes back to the kidneys The water in the blood is lost as urine Geier being so my dear literally pissing it away yeah seriously and that, basically, that's what makes it blood thicker, which leads to poor circulation. It's all it sounds confusing, but it also makes sense in it. Isaac look away, and so the poor circulation leads to its own cascade of problems. Very poor circulation means that you have less feeling in sensation in your extremity. Which means that if you stop your tower cut it open or something like that, you might not even notice so you have a wound, that's left to fester because you're not treating it and then, and then, on top of that, because of the poor circulation, your immune system can't go to the site and help it.

As easily and you are more prone to infections, which can lead to gangrene which can actually lead to amputation or because your blood is too thick to circulate properly right in that poor circulation is also a. Secondly, dear changes and vision is, right. So there is one other thing that happens to there's something called Kido acidosis, which is where your you're metabolism He goes into the fatty acids or the fat cells and cracks him open inserts burning, whatever glucose it can't there's there's this thing called key tosses where, if you're, unlike her at once, diet right where you you it's actually, as far as I can people are concerned, that's like where you want to be right: cause you're, just burning fat cells in your ear

at the buzzing level and you're you're losing way you're not gaining anything you can. Your skull is very prominent is of a beautiful thing right. Your breath is gonna stinky, yet seem a little sweet. Kido ESA doses is not key. Toasts Kido, ass adults, as is its it's the same thing, but to the nth degree, and it can lead to all sorts of big problems caused. The the acidic key tones build up in your liver. I think that can constantly breath you write. It can acetone breath the end. It that can lead to the central nervous system, problems, heart trouble and even that can lead to coma yeah. And harder regularities to its economic. Your body it pretty bad in this is, can be an extreme result of diabetes, which is one of the great reasons its life threatening man. It's a big deal,

Yes. So, as far as monitoring the stuff back in the day, you just said to monitor it every day and some people still do that with the little pinprick and their glucose minors. But now you can have them. You know the built in. Body right. That's actually that's been around a little while says it. If your type one you have to u dont make insolence, are you after injected artificially from our externally right, is like pumps that you can carry around her where that are connected in Europe, that you just press a button and it it delivers insulin. But you have to test to see how much you need at any given time right then, if you, if you put in too much insulin, it's gonna sweep up too much blood sugar, because there's it's not like there is anything wrong with the communication between your insulin in yours, songs with type one diabetes is that you don't have insulin, when you put insolent in your body it does. It goes to work like it's supposed to

So you have to really walk that fine line well in a morally are gonna, be administering it a few times a day to write You got only run your meals right, and you want to make sure that you don't again putting too much or else you're gonna get light headed because your brain cells use glucose and if you have to mention one sobbing up too much glucose, your brain starves in you pass up. Yeah skull, hyper by sea. Mia, like you said, light headed shaky. I think most people with experience such feeling, even if you dont, have like pre, diabetes or diabetes right to set We need people, discoloured low blood, sugar, great, but it's actually probably in yeah. I guess it would be low blood sugar from over abundance of insulin. Yet the item that is when I eat something Super Kirby by.

And I really do that for a lot of breakfast anyway, but if I just like, like a big fat, big old for breakfast and then don't eat again, till dinner, I'll get like little shaky, yet shakes, but it almost feels good in a weird way. You don't talk to me know its ever felt like Now, I'm a high like Ebola, high every once in a while every time, but everyone while strike me where MIKE Shaky but was lighted error. My chest in my solar plexus, second kind, feel it glowing a little bit, and it's almost so much like a weird high interesting MA am I: is it it's not a normal thank Irian. I can speak for myself I do know that, though, if you are feeling light, headed and shaky like that, because this is cuz, your brain is not getting enough glucose and we talked about the brain was one of the specific organs that really needs it. This is when you might see someone drink juice or eat a candy bar or something sweet

I urge you to get that like quick spike, but if it is really really low, you can go into what's called insulin shock where you lapse into a coma that serious business right area, a diabetic comas pretty bad, because all sorts of bad stuff can happen to your brain at that time, so that some, but mostly type point type, two is managed differently, although similarly you have to keep up with your blood you're, not nearly as frequently as you do, a type one but dying exercises like they do say right away like if, even if you well, let's talk a little bit about reverse ability cause. I saw a new study. Ok was here Here's a new study that circled very low calorie diet and six months awaits stability and type two diabetes, and this is on the American Diabetes Association. Homepage and they did a study, basically because his long been thought that, even though they say like you know,

if you really lose weight and exercise really really help. You manage your diabetes, but it's not reversible, like you loud it for life right you have to, He stopped exercising indicting, you exactly develop the symptoms again exactly, but they now say that it is possible with at least for the results of the study and here's the deal was very robust study, was only thirty. People were type two diabetes. I think it was They didn't have a good enough sample of ethnicities, but some of the subjects had diabetes less than for years some had longer than eight years. I found it in this is usually after very, very attic surgery, but they did find the same results of people who just- and this is dramatic, calorie reduction not dislike man and a little better like bury Edric Surgery, level calorie reduction, there

found that immediately after and eight weak low calorie, very low calorie diet. Twelve of the thirty participants had fasting blood glucose levels, normal fasting blood glucose levels and then- and this is the big finding after six months of maintenance, thirteen out of the thirty were able to keep that glucose level below that threshold. That means that forty percent were seemingly, reversible while but they're not making the claim like for sure right by thirty people. That yeah I mean that's, promise ensure that forty per the people that really really lost a lot of weight and a lot less an exercise rival the seemingly reverse early skip it down a normal, but, like you said, if they stopped than it, it might just come right back and that fasting glucose level is is significant. I think we really said, but the aiming at a fast one of the ways that they test for fur diabetes is yeah. You fast overnight. Go to. You

doctor, and they give you a thing of sugar water and you drink it, and then they start testing your blood sugar for several hours afterward and if you don't have diabetes, your blood sugar, comparatively speaking, doesn't spike all that much because insolence working in doing the right thing. So if you have full blown type, two diabetes and you're in the study- and you go take a diet- It is a test and you have regular fasting level, diabetes, blood, sugar, yeah, that's pretty significant for sure yeah. I hope it extrapolate on everybody else. Well will see. Its normally controlled through medication. Oral medication preside, do as they like having to give yourself a shot, a review, our journey, then great yeah, that's that's biggest in theirs, four wasted to do a mere one, one medication, and I guess I just tailored to what your specific case might. They think it might warrant, probably, but one stimulates the pancreas to release more aims: insulin,

no brainer one interferes with the absorption of glucose and by the intestine. One interferes with the absorption of glucose by the intestine ones, improves insolence and sticky. One reduces glucose production by the liver stops glucose NEO Genesis, Ria one helps a breakdown of glucose and the other some literally supplements insulin, which makes me more curious. Like does that mean that if you- and if you inject more insolent and title I believe you overwhelm the insulin resistance or something like that. I don't either. But if you so management is the right word for diabetes, like you have to pay attention to your diet, your exercise, you have to testing, apps out there to help you do that and since were buzz marketing. You me works with a guy who worked with a guy who's. The sea of company called And since we're Buzz marketing, you me works with a guy. I worked with a guy who's. The sea of company called Luke.

The yellow, tee, o o o k o One of many I mean there's a bunch of him, but if you have diabetes is probably the most convenient time for you to keep track of your diabetes is apparently it's a pain to to keep up with that the tests and all the stuff, the data and so Chuck. There's like we said right now. There's, apparently, is possible, maybe to reverse it, but for type one diabetes in particular cause remember, you're, just not producing insulin patient yeah. I saw that this has been around since, like the sixtys, but I'm like it's not new, but I could really find out if it's like the affected nests of it now and like it's working.

Could really find out if it's like the effect, and none of it now and I give its working, isn't working the thank good. If you there was nothing if there is no follow ups on it. That's not, it says, there's show promise, but the big problem was they rejection right where islets, so, basically they go into a deceased donor and they remove their pancreatic islets root. Remember the! were the insulin and the quicker gone is produced. The other sectors. The problem and you put it into a like a syringe catheter and injected into the person with type one diabetes, pancreas and supposedly, though, though, eventually attached to your blood vessel and start producing insulin by, if it that's, if your beard, the body, doesn't reject the donor tissue, yeah, I'm gonna follow up on that cause. I I couldn't find a whole lot about it in time ran short on me, but I do know that it's I mean it.

It's been around legitimately for at least three decades, and then before that with like experimentation, so unannounced seems like they would have firmer grasp on the result by that's all I'm saying it is a little like. I will find out glucose got anything else. Glucose yeah yeah go get. It is pretty clothes, I checked it out. What is it said to me, I know it's like I dont have diabetes, so a lot of it doesn't make sense to me, but right it did from the demonstrate video. It seem pretty robust, yes get and then some if you want to know more about diabetes, go check out this painfully

hey guys want to share some thoughts and comments on the skyscraper part guess so we got a feedback. We got what we get wrong city there. Who cares? It's not like. We were telling people who were going to go purify iron and then try to build a skyscraper out of it. I mean for the number of things that we say: were telling people who were going to go purify iron and then try to build a skyscraper out of it, I spent it. Ok good and we ask for corrections. Ok, do we not think he s it a great job, Josh of summarizing the issue with the figure bases? I e pyramid not being economical for the building owner break you bring their initial investment. Ya said a good job. Bringing up the elevators coincided, allowed the jump and build

to bring their initial investment. You did a good job. Bringing up the elevators coincided allowed the jump in building heights technology would allow us to build nearly tells you want. You should be able to find so unwilling to pay for it that it the difference, however, between iron steel is in fact not that steel is more pure iron. It is iron with carbon added that increases and improves the strength. From its added. In addition, a carbon really carbon and iron. What makes steel steel other elements have relatively minor impact on the properties like stainless steel has chromium said, the really carbon and iron. What makes steel steel other elements have relatively minor impact on the properties like stainless steel, has chromium, etc. There also multiple types of footings, not just

footings, spread footing, spread the load on underlying soil or, ideally rock, because, like you said, the columns going straight to the soil would push right through, but most if not all skyscrapers are so heavy. It's it's so far above the rock instead of spread footings have a deep foundation. This looks very similar to a spread footing from the bottom of the concrete footing up, but then also have columns that reach further into the ground. To increase the resistance to the sinking of this resistance, usually is provided by those columns reaching down a very strong rock. Since we are creating a large table, lots of legs. The whole building is built upon. That is an analogy I can get down with Asia. So look forty come into another Atlanta show MRS Grant Hollis who lives right here. Thanks grants and he went to the pinto, show Great Hollis man of Steel, that's right and grant. I would normally just put on the guest list for tickets, but a man is always tight. Considering

pretty much yeah well, thanks again grant and thank you to your friends and family who show up or even consider some says if you want to get in touch this visit us at home on the website. You should know that com you can find or social all over the place there, and you can also cynicism, so if you want to get in touch this visit, said her home on the website. You should know com you can find or social all over the place there, and you can also send an email to stuff progress along this path: acting coach, Tracy more and I have a brand new podcast spirited actor. My clients include buster rhymes. Fifty cent Lala Anthony and Cardy, be just dame of you ever thought to yourself. How can I learned the craft of acting them? the host of the women. A new weekly pod gas from I hurt radio well interview the kind of women where I dont know

I want to be them or be friends with them, but then, when I realized, I had a voice that I could speak about things that I really care about, whether it's nuclear weapons, whether it's part of depression, I'm too the women now on the radio up an apple podcast or wherever you get your podcast.