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are you looking to the podcast I've Josh Clark. This shows the reach of bright and makes the stuff you should know the facts as economic progress, interim version version one point- well, sir, and your enjoying I guess we can save a lot of beverage, not anymore memory. Usage is blatantly say stuff. You enjoy sparkling water I consider out of CAN Frenchy Pizza yeah. Why are we determined to push it through the envelope and sang and Brandy ETA, it rhymes with the boy third Chuck yeah, you know I was a smoker for one year and One can make a pretty good argument there. I started out

an unreasonably young, a pro european. I was young, you weren't, you know I was young. How old were you pay a picture so first Try cigarette them all young enough so that the the guy who owns the pub in the mall that has the cigarette machine that I'm buying cigarettes, but comes out as a boy. You could do it, but we made off with our cigarettes and smoked one in law. The mall started spinning and everything is crazy. Right isn't that you could smoke in them all the while ago. Here, though, is the first time, the second time was, a few months later great care hand arm my friends, I decided that it was high time we started smoking, so we pool never mind together and ended up with enough. We figured for ten packs of cigarettes, so everybody gave me money. I gotta my bike and rode to the gas station rode up on my bike,

cash. You saw me kid he's thirteen right upon his bike. No fourteen just turned put it down and walk in and go. I want to impact the cigarettes assorted. The sort of red likely event like a cool about Marlboros about can't de arouse like anything like that were lying Islam, and I remember the cashier just like. Ok, he go kid and sent me off with a bag of Tampax cigarettes, Daniel from the handlebars of my bike. Sprightly ten bucks to it was about time I'll check it back in the day and we get back, the words are both like all my god. We started a smoking and like right off the bat. I started smoking tons of cigarette, were you inhaling yeah you and I Green got sick and still was like. I like this a lot and smoked for twenty years. That is not in shock. Today is April, twenty eight and how many days are there in April thirty

thirty one guess thirty one, I'm gonna go with thirty one two and I am going to say not thirty. In three days I may first ill be one year since I've really do it with a lot of time. Kicked it congratulations. I spoke to you depriving never even share that. I had no idea that, yes, yes, in college, like everyone does here and there, when I colleagues is here, but it was ever anything that got its nicotine never took hold to where I needed a cigarette. It was always very much a social thing and then, when I run Europe. Of course, I rolled my on cigarettes and follows the super cool yeah, but you know it kids, I was not go. I don't know. I thought I wanna. I want to add that to theirs Absolutely nothing cool about what I did there's nothing adventurous. Many many many times over the course of my life. I cursed myself a curse that Kashmir and having cursed my boy,

before allowing me to make one of the worst decisions of my entire life. The I regret it time and time again you cursed Abraham, Lincoln, because he was on the two five dollar else if you know it, asked the tape or not probably he was on the pennies that were used to pay prior ten taxes, cigarettes so and nicotine got under my skin chuck as it were, which is one of a few ways they can diffuse into the human body. This right should we talk about tobacco for its second here, let's at the beginning, it was cultivated is earliest six thousand BC, people chewing on or inhaling tobacco. They realize hey. This is pretty good yeah native Americans, I'm not sure what tribes they used to roll

like cigars, that were several feet long and somebody would hold it at the end, maybe another one in the middle and you'd walk up and you'd puff item like really hard and inhale and answered coughing and then from the coughing you get light headed in supposedly had a vision interesting? Well, I do know that as early as the sixteen hundreds people actually thought, you know what this might be bad for you in a betcha there's a link here to some of these diseases that are killing people in the smoke that where inhaling yes- and I did know that it had no idea- went back that I didn't neither concerns about smoking right in in the cancer. Apparently they were aware of the cancer back then as well yonder. They frighted, probably colored, like spirit intrusion by yeah. There they they knew that there is something to smoking. They also thought it was medicinal which, as will see towards the end of his podcast, has actually made something of a resurgence near the middle,

properties of nicotine. So this is nicotine, go mink, yonder tobacco, yes, nicotine! Ah, Nick Nick Oceana back what did I say nothing to try as IRAN. I like your when Chuck. Thank you making to become back these days. It is so I need a teen. Josh is a liquid alkaloid. Yet the only want most out later white, solid, thrilling clink. Having a cake, I saw a page that that nicotine, the only liquid or I believe that it is an organic compound. Alkaloid is, and it's made of carbon hydrogen nitrogen and sometimes a little oxygen in there, and sometimes why and nicotine makes up about five percent of the tobacco plant if you're Talkin weight, but cigarettes contain between eight and twenty milligrams of nicotine purse cigarette, but here's an important distinction. You

in just about one milligram of that into your body. When you smoking, cigarettes is absorbed you in just more, but only about a milligrams, yellow deploying I'd, say in latin check. Ups, from which he had so, like, I said, make a tea under my skin, which is one of three ways that it can be absorbed right through the skin. In the lungs and mucous membrane, like the lining of your nose in gums, and if you think he would snort tobacco, that's a tough was, and is the man to sniff snuff the dates they still make that stuff they viewed. It's a real timely, like I think you can only find it. It.

The customer service, counter to Piggly Wigley, and it's still there from my grandfather's company, actually made snuff in Tennessee your grandfather, Archie Ronald. Now he didn't on the company, but user, like of four manager of the left, the workers on the floor. I think I gotcha so he exploded Yes, now tell me like candy, popcorn and stuff is weird. Thomas company sit made all kinds of crazy things. Well, it was not our generals. Oh nicotine, and we're talking about how it how it gets into your body its absorbed. It moves into the the blood vessels that line these tissues straight into the bloody and then pretty much directly to the brain were. Does its way imo effects right right out of the ways that you can ingest nicotine into the body. The lungs are the most efficient right, which is whether cigarettes the riot exactly the inhaling nicotine through smoking. Tobacco

introducing this, this drugs alkaloid to the elderly or lie which are the little tiny ersatz where gas exchanging occurs. Yes- and this is the fact of the pod cast for me- ok muttered, the AL, the all I write little millions of tiny little gas bags cute little gas back very clear. If you combine their their surface area the total surface area, they have ninety times more service area than the human skin. I met in a second average sized person, but still it's pretty impressive, yet which again is why people smoke it and we were gonna, say cigarettes a lot, but obviously this includes cigars and pipe smoke, and anyway you're gonna, ingest tobacco, dip snuff. If you're still doing the snuff, read the snuff so but we're gonna say cigarettes, mainly that's fine, that's the most popular way. I believe that's right now,

these resolutions are very, very difficult to keep get more exercise save more money. What about this? We have a resolution that you can really work with stop wasting time going to the post office that right you stamped out I'm instead because they bring all the services of the Eu S postal service right to your computer with yours business, sinning invoices or packages or an online seller shipping out products stamps that can handle it all with ease yank it. This was simply come. You get five cents off every first class Stamp in up to forty percent of priority mail, this right? U S posted twenty four seven for any letter any package any class anywhere. You want to send it, there's no risk and our promo code, ass, white, ass, gay you're, gonna get this offer afore weak trial, plus free postage, and Digital scale, and there are no long term commitments or contracts just go to stamp that come click on the microphone.

Top of the page and type in s. Why, as K that stance, I come from a goat s. Why, as K stamps that come never go to the polls office again, Sir Joshua, said here's the years an interesting thing too, about the half life. Is that right? Is it how half life works? It said that nicotine has life of sixty minutes so six hours after cigarette that one program that your body is now point o three one, the dancing quite right, but I guess it is. I don't know chuck well that's what it says. So that's what we're gonna go, but how does your body get rid of this stuff? How does it process for removal several ways. Eighty percent of it is broken down. Your liver? Ok, some is matter. Raised by your lungs to in turn into coding and nicotine oxide

yeah. Encoded Nina looked up, it's an alkaloid as well and also anagram for nicotine, and it does pretty much the same thing as nicotine. Just at a much lower potency catcher in alkaloids by the way tend to really mess with humans, like of theirs different types. Alkaloids put the under the large umbrella alkaloids. You have strychnine night, Shade Opium Civil Simon, Hemlock AIR got anything they can get you wasted, Orton kill! You right, isn't alkaloid basic right. You can also get rid of a coat mean through urine you, so it takes about twenty four hours to get rid of company that way, so you can actually a negative p test yelling about a day after or within a day. You can also do smelters that works to the breath for them closer the hare. Whatever here's. The fact that the package for me Josh is that. Some people have a genetic defect in the Indians.

Liver that, Meudon enzyme is less effective, it metabolizing nicotine, so some people are born, able to smoke less yet retain the feeling they get from smoking. Longer. There's a time in my life when I would have called people lucky yeah. Well, I mean I guess: if you're gonna smoke, it's better to smoke less, but Odin should mess with it at all. Agree Chuck, agree, Socrates, eighty things these to say how much loved cigarettes I know, but I still think in this one, even if I did still smoke I would I would advise never to take it up shock us talk about the effects of nicotine. It isn't alkaloid, which means its drug. Basically, I'm, which means it has an effect on a couple of parts of the brain right. Yes, and not just the brain of the body or the first response is the body has

to nicotine is the release of adrenalin which kicks in our dear old friend the fighter flight response right. Yes, then, that's initially, but can also where they called by phasing yeah. I can invigorate and relax in. That sounds a little I'd until you think about like something like alcohol, which has the same qualities many times, which is why now. The girl at the bar as all fired up at first they are later on its way to the reason why a dry- or you know I can't hold my head up. The last couple shows the last couple comedy shows I've been too there have been chatty drunk girls who have just been overly courageous in expressing what was on their mind loudly at any given moment, heckling or destroy but heckling, but not not heckling like you're, a big meaning dislike

the guy. We had only joking tubular, I work at home. We know, is the hike here, you're Talkin bout, gold, three right now in writing, idea. What he's gonna do that Galifron access and classic gaiety bits, then, with hecklers, this wonderland, Slade Thrilling, get everyone. I've. Seen, though, has done a pretty good job with these people source for the jump from one imagines so Chuck. Ah, you ve got the release of adrenalin hum you also. We have an explanation for white people who smoke tend to eat less yeah you here or fixation, and I imagine that that probably has a lot to do with people putting on the weight everyday quit smoking bright. But if you smoke, you can go

fairly long without food? And now we understand why nicotine send some signals to your brain right here. Let me do it a little dramatically, nicotine through the body he body go ahead and dump allotted glucose stores, yourselves into the bloodstream. Ok, yeah bodies is ok and the naked thesis invite away. I don't want you Placing any insulin, insulin absorbs glucose in the bloodstream and vice like ok, and then the nicotine Gus okay. Well, now that you have a bunch of glucose in your bloodstream, dont think that you just eaten in our full and the body goes. You know I do and the insolent us you got actually. Rather he and yes it s called Hyper Glassy Mick and, like you said, basically it it makes you

Feel like you're not hungry, and it also increases you're basal metabolic rate, so you're gonna burn more cow he's sitting around smoking, then you what, if you're sitting around- and this all sounds awesome what I eat less and I d burn calories sitting around sounds awesome, but enforced it's not like. Oh, I can lose weight. Smoking in us like exercise because which are actually doing is killing yourself over the long, all right in speaking of basil or basal metabolic rate. That is something that apparently very overlooked when with people who exercise and count calories and things like that, how do the edges suddenly Sylvester the cap for you? If you exercise any burn five hundred calories people are like. Well, that's pretty awesome. I defer five hundred college but they're not take.

Account the basal metabolic rate which is head you just not going to the german state home. You burned a hundred fifty dollars so really only burnt three hundred fifty calories. Yet to take your neck calorie burn to really think about how much weight you lose exercising here. Why don't ever look at them like a treadmill on ever pay attention? like you burn this many calories. I don't either. I do see oversee I answered. Like you know. I gave my hard work out for forty five, exactly they didn't follow her dead exam and I never way myself either idea. Do you really yeah? It's my scale, actually the batteries or fix it. I put a battery and fit and it had been out for likes for five months and I didn t know I felt myself getting fatter and await myself, and I was actually like a pound lesson. I was six months ago sales creatures on ahead. What's not Kate, ideally I'm twenty pounds less than I was six months ago. I've just been reintroduced.

Bones. Lately. Yeah, that's good guess are wherein the M puckers. You haven't noticed side, okay, so shock. Cigarettes will kill, you is where we left off, because they will raise your back cholesterol level your arteries and eventually you're in line for a heart attack or struck yes and that and we will get into a later suck at the brain yeah. I don't think that's mischievous spoiler. Now cigarettes kill annually. The the irony of it is The nicotine won't kill you I mean the nicotine can kill you, but you literally have two overdose on it and it takes more than you could get from cigarette. Yes, its other chemicals of thousands of other camel in a cigarette that kill you. Well, I'm glad he said that cassettes, a huge point. The other chemicals are killing you, the nicotine is what makes

smoke over and over and over again. So it's it's a one to punch of death. Well, let's talk about that talk about what happens in the brain. That gets you basically addicted. First up, as with anything, is the reward path, Why is manipulated right so just like with cocaine or alcohol or anything like that dope means released, which is how we learn, how to eat and reproduce do anything sir. The causes our own or our species survival were rewarded right. Yes, well, nicotine unlocks the release of dopamine, which teaches us to smoke again right attract. But even more than that, a smarter, neurotransmitter and I'd. You can't think that dopamine kind of a dome fat, Chris Farley Kind of euro transmitter. You know the kind of like our good ties: sharing a sea

Colleen, like a slick, that's a Patrick Bateman kind of neurotransmitter. That's right and nicotine docks to this- that binds to this neurotransmitter and that's were that's where it all happened. Basically in man and reject police are Ip Chris Farley. I know for a fact that he was not dumb. He was a very smart guy. Yes, I was talking more about his a buffoon light characters that rightly Not him specifically, they want to speak ill of the dead. If Iceland, I Chris far, that's right, so we just mention the sea to call in which the nicotine binds to this neurotransmitter. It's gonna end when he spoke is gonna. Greece the release of a single Colleen, and the problem is that this euro coins, rate in the body, thereby love the body, regulates the release of it in the proper way, but when Nick gets involved is just out of control, Willy nilly the seed of calling going crazy in your body right what it is

bunch of a seal calling being released, means a bunch of activity in the colony Ergic neurons right. So the Kohen Ergic neurons basically tell your body like hey wake up, but let's go do something right: let's go roller skaters, thing like that call energetic neurons, also promote dopamine release the applicant so you're up an atom, you're feeling good you're feeling euphoric. You endorphins are released, which is the it is natural painkiller, yet further the runners high, that is endorphins, going crazy at the end of your long jog, exactly and then lastly, That cement at all is the release of glutamate, which glutamate has been shown to enhance neural connections. Connections between the neural pathways, which enhances memory. Remember. We talked about memory that right. We didn't talk about gloomy yeah, how do we measure it hurt now? Well, what can happen here is if you, when you ingest nicotine glutamate, can

a memory loop of how awesome it is- and I got this recurring I'm playing in your head like smoking. Great smoking great haven't cigarette over and over and over a deadly concoction. Yes, so that's what happens if you lose weight, you feel great faggot, like he said what you're slowly dying. Yes, but we mentioned earlier that there there there are medicinal this medicinal value to nicotine, specifically right, yes, because it has its effect on your college pathways. It could help with Alzheimer's their finding. Alzheimer's is a loss of Colin Ergic Neurons right, which leads to memory loss. That kind of thing you not quite as active, you are angry and you dont know why right betrayed their finding that nicotine can help replace these or

It can, at the very least, stop the loss of coal, energetic, neurons and promote the activity of the ones that are still around the tripe. Hence reversing the effects of Alzheimer's oars. Forestalling that's right in direct syndrome is another thing there. Looking into now with nicotine patches slowly delivering nicotine can reduce the episodes of threats text an outburst so that we can. I don't even if we cover that internets. This may be news to us. Yes, the anyone who hasn't her turret syndrome yet go back illustrates again on net is by Chuck again we want to specify that you are much more likely to die from ingesting nicotine via the current ways we have it. We have two ingested than you are

gain any kind of benefit right. The tri cancer, obviously Emphysema heart disease stroke and the nicotine is what gets you addicted and all the thousands of chemicals in the cigarette is what tat kills you and it will kill you I mean if you smoke your whole life. You're, very much of a rarity. If you're one of those people, that's like smoking for fifty years and not suffering any ill effects that smells really rare. Sometimes I feel death over my shoulder really now you're healing man you get, you can reverse the effects. This was so good about it. Yet you can reverse the effects, but you can also do lasting damage his well that they also its time bombs in your body after smoking. Thousands and thought the cigarette over twenty years. True, but you? U dont goodbye! Here's the thing: saving money with Geico was almost better than playing pick up basketball is always that guy who joined your game, He never passes the rock he

instantly bricks theories and who can we have you and then put his hands up and say no foul, no foul with Geico it's easy to switch and save on car insurance. No need to fake an angel sprang because you're absolutely exhausted, so which in save with Geiger it's almost better than sports, I'm so check. We talked about it being psychologically addictive right, very much, you do it compulsively. They definition of this. Is U R compulsive engaging in an activity that you know will harm you. Yes, you're still doing it. Yes and it is physiologically anything neuroscientist basically say anything that that.

Synthetically turns on your reward. Pathway is addictive, Breton and that cigarettes for sure, yes or nicotine specifically, and we also mentioned checkers- that nicotine itself is harmful if you overdose ANA Maria but is very difficult overdose. I can remember, there's eighty twenty milligrams of nicotine and cigarette by your body only in just about one, it's very difficult to overdose by way of smoking inhalation. It is, but if your baby, in your dumb, you can eat cigarettes? Are cigarette butts, yes and overdose on it? It doesn't he very much it can take eating one cigarette can send a baby to the hospital with a lot of problems. Yes- and I looked and then it says on this article, but I double checked the adults if you eat like the seven cigarettes as an adult. You will likely die so

don't ever eat a cigarette. For any reason, never remember. We talked about ambient people on ambient air waking, I wanted to buy cigarettes here and now surprise. I thought it was like. Oh, I like three packs of cigarettes and you might get really sick, but if you eat for five six cigarettes, you will likely that if you don't get to a hospital so there this all reminds me of a story of. I hope somebody out there can help me with this. It was in a feature article in June, you some time between, probably nineteen, ninety and ninety. Ninety, four, ok, it was about a bank robber mayor. He was one of the more successful bank robbers of all time because he figured out if you put a cloud we're gone glasses and then dangle ribbons from the glasses. No one will ever be able to give a good description of you ever if there is a very successful bank robber for awhile, what about is wearing a mask,

while the other was the headings, ok, this guy finally get snapped and right and is in prison, and he decides he needs to get out. So he takes a pack of cigarettes right that I imagine he treated if you honey buttons, for he unrolls cigarettes and put them in a cup of water lets a couple, or sit overnight goes around out into the prison. Your dream, like exercise time, runs around a couple of times. Comes back in immediately chugs this cup of eighteen, water of tobacco water and falls right over right yeah. So the hospitals like weaker the prisons like we gotta, get scared hospital. Well, the ambulance that shows up is full of paramedics who pull guns on the prison guards get the guy in the back of the angels. It's his gang, posing as paramedics. They taken do an underground doctor who revives him and he lives. Is that that really happen

according to the secured in my memory, you article her that's what happened I we can find out about, but we can explain exactly what they would have treated him with tee to overcome this nicotine overdose, which he was shortly suffering came. We can now well what would they treated less? Well, there's a couple of things you could do. You could get that you can get the nicotine out by giving an Ep Cac something to induce vomiting, yeah sure, which you really want to do. You could also whom activated charcoal which the carbon will attract the nicotine alkaloids and will keep the body from absorbing more of but that's precisely, what you want to do is to get out whatever you can and make sure nobody, each anymore, nicotine yeah- and I guess they only scenario known- would want to do. That is the the sleepy hung over warning after when you reach over and grab what you think is that cup of soda, and it's really that,

they all your cigarette, pathetic this girl. I knew a kid who had still drink beer with cigarette button. It smart, So I am not talking about the threat of Christian. I so nicotine we said it gets in your body like any drug. Your body will adapt, adapt, adapt to that drug and start behaving differently. So that's why, when you quit D any drug your bodies say wait a minute like I was functioning, on a certain level here and I just took the nicotine away, so I don't know what to do. I'm used to a certain amount of color color jack activity here. Give it to me, so I'm gonna be really messed up for a while and you're gonna be really irritable, Mr Persson, who, who has my body and

you're gonna be anxious. You're gonna be depressed and you're gonna crave me a lot for about a month and beyond, but a month physically, they say is when it can have will leave your system but the psychological part. I know some people that quit smoking for a decade and they still create that cigarette. On occasion I used to, I would meet people here there. Who would you know he saw me smoker, like I quit two years ago, and I still want to cigarette every day- and it scare me some kind of like I think I'd rather die than go. They live like that. You know yes, here is, and now I understand what they're talking about where it's like it, it's so manageable, passing thought that I know I know but every day, but I mean I have had it were like- would be really great. What are your triggered? Locust cigarette probably having a drink that for a lot of people

alcohol cigarettes are you think so now I haven't noticed any actual triggers and there is a lot of it is association like yes, if you, if you drink, you write one. Oh you want a cigarette that doesn't as fleeting it's more kind of out of the blue, not like stress, related, not necessarily interesting. It's just kind of their rights, in particular, underneath the certain party, your brain and it's kind of flow to the service everyone's wildly kind of bad it away rights completely men out you well that's good, it's different for everybody and on the way it reacts in your body is different for everyone, tolerance level is gonna, be different for everybody. That's why some people smoke three facts a day is because they need to keep recharging that head of government in some people can get by with smoking. The occasional cigarette in our vices did not ever start avoid the whole mess, and this is coming from a dude who loved the smoke and now you're dislike

No, no! No, this great a shock. If you love nicotine- and you want to learn more about it, if you love it an intellectual level, I guess what I mean you can learn more by typing in lick teen. I guess I imagine you could also typing coding me. If you want to see in the search bar has worked, I come which will bring up decline, nicotine and search bar brings of listener male! That's right! You almost got me. I've got a slick Joshua. You call this. Upon wacky wills, yes, where's for wacky will stories in this was a good one. This is for a minute. Gales Burg, Illinois, Dear Joshua, Jerry guys have been a big fan for years. I heard how wills work. I was hoping you admission.

They would story of strange will stipulations, but you didn't so here it is, and he included a link to snobs, because its true. Yet he was the only one to sentence on into the more than one s comment. I think so the Toronto lawyer name Charles Van Similiar, died and nineteen. Twenty six of the heavy estate left a number of strange clauses in his will, most of which are described in the link, the strangest of which is came to be known as the great store Derby lackey, can He left a significant portion of his money. Investment there turned out to be worth of the seven hundred and fifty thousand dollars to the woman who gave birth to the most children in Toronto and the tapes hotlines debt. As you know, I don't know I'm really trying to think of a reason he was. He was a big fan, coitus, maybe or

find a populated Canada against take over the? U s once and for all the Toronto. He says There were a number of interesting legal challenge is highlighted in the lake such as whether or not the legitimate or deceased children counted and ultimately the purse was split among six women in total the most one again before women with nine legitimate live births during the timeframe, each of whom receive a hundred. Two hundred of you guys have the chance to mention this uncommon and preaches equipment for mate. Gilbert and quickly. We also want to mention Chris The marine was a marine and then wait a Naval reserve officer and they were required to Well, so we mention the on the battlefield type the wheeler or a well yeah

Apparently now you have to prove that you have the will to get into the answers itself as information we got from Chris. I stress- and I cant remember the name of the person who is an email in utter disbelief that we failed to mention millions, but my apologies to that person. If anyone else, you thought the same thing we totally overlooked. That's lesser prior goods but lesser prior and jointly address is exactly. Do you want to say hi to checkers or me? Are you can do so by going on Facebook, page facebook, dotcom snatched up, you should know, I'm? U can also tweet high to us. That's at as why escape I cast, and then you can always send us.

Fasten email at stuff, podcast at Housetop works not come for more or less than thousands of other topics. This house up works. I come to learn more about the podcast click on the podcast cycle in the upper right corner of our hope, is the House of Lords Iphone have has arrived download it today on Itunes brought you by the way, twenty, two thousand twelve Camry, it's ready are you. We are living in complicated times. I'm seventy rule MSNBC Anchor and NBC Newscorp and in my new plug cast modern rules, I'm gonna be time unpacking some of the Harry's of today's top I decided I want you survived survival. I spec equal aboard. They won't need its american listen and subscribe to my new podcast modern,

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